PMID- 9736059
OWN - NLM
STAT- MEDLINE
DCOM- 19981002
LR  - 20190915
IS  - 0148-639X (Print)
IS  - 0148-639X (Linking)
VI  - 21
IP  - 10
DP  - 1998 Oct
TI  - Cortical excitability in patients with essential tremor.
PG  - 1304-8
AB  - We used transcranial magnetic stimulation in 10 patients with essential tremor 
      and 8 matched healthy subjects. A round stimulating coil was placed over the 
      vertex and electromyographic activity was recorded from the first dorsal 
      interosseous muscle. Paired transcranial stimuli were delivered at interstimulus 
      intervals of 3, 5, 20, 100, 150, and 200 ms. The intensity of the conditioning 
      stimulus was 80% of motor threshold at short and 150% at long interstimulus 
      intervals (ISIs). We also measured the silent period obtained after a single 
      magnetic pulse delivered at 150% of motor threshold during a submaximal muscle 
      contraction. Patients and controls had similar motor threshold and similar 
      latencies. Paired magnetic stimuli given at short and long ISIs at rest, and 
      during a voluntary muscle contraction, elicited similar responses in both groups. 
      The silent period evoked by transcranial magnetic stimulation had a similar 
      duration in patients with ET and controls. In conclusion, these findings suggest 
      that patients with essential tremor have normal cortical motor area excitability.
FAU - Romeo, S
AU  - Romeo S
AD  - Dipartimento di Scienze Neurologiche, Universita degli studi di Roma La Sapienza, 
      Rome, Italy.
FAU - Berardelli, A
AU  - Berardelli A
FAU - Pedace, F
AU  - Pedace F
FAU - Inghilleri, M
AU  - Inghilleri M
FAU - Giovannelli, M
AU  - Giovannelli M
FAU - Manfredi, M
AU  - Manfredi M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Muscle Nerve
JT  - Muscle & nerve
JID - 7803146
SB  - IM
MH  - Aged
MH  - Electromyography
MH  - Evoked Potentials, Motor/physiology
MH  - Female
MH  - Humans
MH  - Magnetics
MH  - Male
MH  - Middle Aged
MH  - Motor Cortex/*physiopathology
MH  - Physical Stimulation/methods
MH  - Reaction Time/physiology
MH  - Reference Values
MH  - Tremor/*physiopathology
EDAT- 1998/09/15 02:03
MHDA- 2000/06/20 09:00
CRDT- 1998/09/15 02:03
PHST- 1998/09/15 02:03 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1998/09/15 02:03 [entrez]
AID - 10.1002/(SICI)1097-4598(199810)21:10<1304::AID-MUS9>3.0.CO;2-F [pii]
AID - 10.1002/(sici)1097-4598(199810)21:10<1304::aid-mus9>3.0.co;2-f [doi]
PST - ppublish
SO  - Muscle Nerve. 1998 Oct;21(10):1304-8. doi: 
      10.1002/(sici)1097-4598(199810)21:10<1304::aid-mus9>3.0.co;2-f.