PMID- 9748094
OWN - NLM
STAT- MEDLINE
DCOM- 19981209
LR  - 20220317
IS  - 0031-9384 (Print)
IS  - 0031-9384 (Linking)
VI  - 64
IP  - 3
DP  - 1998 Jun 1
TI  - Short-term effects of macronutrient preloads on appetite and energy intake in 
      lean women.
PG  - 279-85
AB  - This study investigated the relative satiating hierarchy of the four 
      energy-providing macronutrients (fat, carbohydrate (CHO), protein, and alcohol) 
      in lean women. On four separate occasions, the composition of an iso-energetic 
      lunch preload was manipulated in 12 lean (BMI < 25 kg/m2) women. The four 
      treatments comprised a 1-MJ baseline meal and drink (40% fat, 48% CHO, 12% 
      protein) to which was covertly added: 1) + 1MJ protein; 2) + 1MJ alcohol; 3) + 
      1MJ CHO; and 4) + 1MJ fat. Prior to and at 30-min intervals, subjects completed 
      100-mm visual analogue scales rating subjective hunger and satiety. Ninety min 
      following the preload, an ad lib. lunch meal was given (40% fat, 48% CHO, and 12% 
      protein) and energy intake (EI) measured. Energy intake at the lunch meal was 
      2195 (880, SD) kJ, 2772 (1191, SD) kJ, 2502 (681, SD), kJ and 2558 (1050, SD) kJ 
      for the protein, alcohol, CHO, and fat preloads, respectively. There was no 
      significant difference between the pleasantness of the preloads (p > 0.05). 
      Macronutrient composition had a significant effect on short-term hunger (F = 
      3.19; p < 0.05), subjects being less hungry after the protein preload. Subjects 
      also had a lower energy intake after the protein preload (F = 3.11; p < 0.05). We 
      conclude that only protein has a differential short-term satiating effect when 
      incorporated iso-energetically and at a similar energy density into the diet.
FAU - Poppitt, S D
AU  - Poppitt SD
AD  - MRC Dunn Clinical Nutrition Centre, Addenbrooke's Hospital, Cambridge, UK. 
      S.Poppitt@auckland.ac.nz
FAU - McCormack, D
AU  - McCormack D
FAU - Buffenstein, R
AU  - Buffenstein R
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
RN  - 0 (Central Nervous System Depressants)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
RN  - 3K9958V90M (Ethanol)
SB  - IM
MH  - Adult
MH  - Appetite/*physiology
MH  - Central Nervous System Depressants/*pharmacology
MH  - Dietary Carbohydrates/*pharmacology
MH  - Dietary Fats/*pharmacology
MH  - Dietary Proteins/*pharmacology
MH  - Eating/*physiology
MH  - Energy Metabolism/*physiology
MH  - Ethanol/*pharmacology
MH  - Female
MH  - Humans
MH  - Hunger/physiology
MH  - Middle Aged
MH  - Satiety Response/physiology
EDAT- 1998/09/25 00:00
MHDA- 1998/09/25 00:01
CRDT- 1998/09/25 00:00
PHST- 1998/09/25 00:00 [pubmed]
PHST- 1998/09/25 00:01 [medline]
PHST- 1998/09/25 00:00 [entrez]
AID - S0031-9384(98)00061-4 [pii]
AID - 10.1016/s0031-9384(98)00061-4 [doi]
PST - ppublish
SO  - Physiol Behav. 1998 Jun 1;64(3):279-85. doi: 10.1016/s0031-9384(98)00061-4.