PMID- 9758872
OWN - NLM
STAT- MEDLINE
DCOM- 19981216
LR  - 20061115
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 15
IP  - 5
DP  - 1998 Oct 10
TI  - [Detection of Hep-2 and hepatoma cell line chromosomal aberration by using 
      fluorescence in situ hybridization].
PG  - 278-80
AB  - OBJECTIVE: To study the chromosomal aberration of hepatoma cell line (1172) and 
      laryngocarcinoma cell line (Hep-2). METHODS: Fluorescence in situ hybridization 
      (FISH) was used with nine chromosomal special libraries. RESULTS: The abnormal 
      signals indicated that very complicated aberrations existed in the two cell 
      lines. This suggested that the aberrations also existed in other chromosomes not 
      yet studied. In 1172, the major type was structure aberration, but in Hep-2, 
      numerical abnormality was shown in almost all chromosomes studied. CONCLUSION: 
      Compared with traditional cytological methods, this technique has the advantages 
      of being quicker and more accurate and sensitive.
FAU - Pan, S
AU  - Pan S
AD  - Department of Biology, Najing Normal University, Nanjing, Jiangsu, 210097 P. R. 
      China.
FAU - Zhang, X
AU  - Zhang X
FAU - Wang, F
AU  - Wang F
FAU - Zhao, W
AU  - Zhao W
FAU - Li, C
AU  - Li C
FAU - Chen, Y
AU  - Chen Y
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
SB  - IM
MH  - Carcinoma/*genetics
MH  - Carcinoma, Hepatocellular/*genetics
MH  - Cell Line
MH  - *Chromosome Aberrations
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Laryngeal Neoplasms/*genetics
MH  - Liver Neoplasms/*genetics
MH  - Tumor Cells, Cultured
EDAT- 1998/10/06 00:00
MHDA- 1998/10/06 00:01
CRDT- 1998/10/06 00:00
PHST- 1998/10/06 00:00 [pubmed]
PHST- 1998/10/06 00:01 [medline]
PHST- 1998/10/06 00:00 [entrez]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Oct 10;15(5):278-80.