PMID- 9759536
OWN - NLM
STAT- MEDLINE
DCOM- 19981120
LR  - 20190512
IS  - 0379-864X (Print)
IS  - 0379-864X (Linking)
VI  - 23
IP  - 4
DP  - 1998 Aug
TI  - Heterogeneity in the accessory olfactory system.
PG  - 477-81
AB  - The mammalian accessory olfactory bulb (AOB) is chemoarchitecturally 
      heterogeneous in that it stains differentially with a number of markers; the 
      receptor cells that project to the AOB are similarly heterogeneous. What is the 
      significance of this heterogeneity? We have found that the AOB of the gray, 
      short-tailed opossum, Monodelphis domestica, stains differentially with a number 
      of 'markers': antibodies to olfactory marker protein (OMP) and the alpha subunit 
      of the G protein Gi2, the lectin of Vicia villosa and NADPH-diaphorase. These 
      markers stain the rostral AOB more strongly than the caudal AOB whereas, the G 
      protein subunit G(o) alpha is located predominantly in the posterior subdivision 
      of the AOB. This heterogeneity in the chemoarchitecture of the AOB may reflect a 
      fundamental organizational dichotomy within the vomeronasal system that 
      corresponds to a functional dichotomy. The vomeronasal sensory epithelium also 
      exhibits a chemoarchitectural heterogeneity: receptor cells in the basal third 
      are G(o) alpha-immunoreactive whereas the cells in the middle third are Gi2 
      alpha-immunoreactive. Tracing studies using WGA-HRP demonstrate that the neurons 
      in the middle third of the vomeronasal sensory epithelium project their axons to 
      the anterior AOB whereas those in the basal third appear to project to the 
      posterior AOB.
FAU - Halpern, M
AU  - Halpern M
AD  - Department of Anatomy and Cell Biology, SUNY Health Science Center at Brooklyn 
      11203, USA. mhalpern@netmail.hscbklyn.edu
FAU - Shapiro, L S
AU  - Shapiro LS
FAU - Jia, C
AU  - Jia C
LA  - eng
GR  - DC02745/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PT  - Review
PL  - England
TA  - Chem Senses
JT  - Chemical senses
JID - 8217190
SB  - IM
MH  - Animals
MH  - Cricetinae
MH  - Mice
MH  - Olfactory Bulb/*physiology/ultrastructure
MH  - Opossums
MH  - Rats
RF  - 32
EDAT- 1998/10/06 00:00
MHDA- 1998/10/06 00:01
CRDT- 1998/10/06 00:00
PHST- 1998/10/06 00:00 [pubmed]
PHST- 1998/10/06 00:01 [medline]
PHST- 1998/10/06 00:00 [entrez]
AID - 10.1093/chemse/23.4.477 [doi]
PST - ppublish
SO  - Chem Senses. 1998 Aug;23(4):477-81. doi: 10.1093/chemse/23.4.477.