PMID- 9774808 OWN - NLM STAT- MEDLINE DCOM- 19981218 LR - 20131121 IS - 0210-0010 (Print) IS - 0210-0010 (Linking) VI - 27 IP - 157 DP - 1998 Sep TI - [Effect of biscuits fortified with haem iron on the intellectual status of pre-school children]. PG - 400-4 AB - INTRODUCTION: In undeveloped countries such as Peru there is a high prevalence of ferropenic anemia. In addition, iron deficiency produces cognitive alterations that could be corrected by iron treatment. OBJECTIVE: To evaluate the effect of administration of heme iron-fortified cookies on the intellectual status of preschool children. PATIENTS AND METHODS: Using the Goodenough-Harris Test (GHT) and Wechsler Preschool and Primary Scale of Intelligence (WPPSI) we studied the intellectual status of 53 children who received heme iron-fortified cookies for 6-8 weeks and 55 controls without fortification, in 2 occasions (before and after intervention). RESULTS: We observed a significantly higher improvement in children who received iron respect to controls for GHT score (p < 0.001), WPPSI score (p < 0.05), WPPSI attention-concentration subscale (p < 0.01) and WPPSI pure attention subscale (p < 0.05). CONCLUSION: Administration of heme iron-fortified cookies may improve the intellectual performance of low-income preschool children. FAU - Salinas-Pielago, J E AU - Salinas-Pielago JE AD - Ministerio de Salud de Peru, Lima, Peru. FAU - Vega-Dienstmaier, J M AU - Vega-Dienstmaier JM FAU - Rojas-Oblitas, M AU - Rojas-Oblitas M LA - spa PT - Clinical Trial PT - Comparative Study PT - Controlled Clinical Trial PT - English Abstract PT - Journal Article TT - Efecto de las galletas fortificadas con hierro heme sobre el estado intelectual en preescolares. PL - Spain TA - Rev Neurol JT - Revista de neurologia JID - 7706841 RN - E1UOL152H7 (Iron) SB - IM MH - Anemia/*therapy MH - Child, Preschool MH - Cognition/drug effects MH - Female MH - *Food, Fortified MH - Humans MH - Infant MH - Intelligence/*drug effects MH - Iron/*pharmacology/*therapeutic use MH - Male MH - Peru MH - Wechsler Scales EDAT- 1998/10/17 00:00 MHDA- 1998/10/17 00:01 CRDT- 1998/10/17 00:00 PHST- 1998/10/17 00:00 [pubmed] PHST- 1998/10/17 00:01 [medline] PHST- 1998/10/17 00:00 [entrez] PST - ppublish SO - Rev Neurol. 1998 Sep;27(157):400-4.