PMID- 9775289
OWN - NLM
STAT- MEDLINE
DCOM- 19981029
LR  - 20190724
IS  - 0022-2151 (Print)
IS  - 0022-2151 (Linking)
VI  - 112
IP  - 7
DP  - 1998 Jul
TI  - Serum antibodies to human herpesvirus 7, human herpesvirus 6 and cytomegalovirus 
      in patients with idiopathic facial nerve palsy or sudden deafness.
PG  - 617-21
AB  - The aetiology of idiopathic facial nerve palsy (Bell's palsy) and sudden deafness 
      are not known, although viruses have been suspected as a cause of them. We 
      investigated the relationship between Bell's palsy or sudden deafness, and 
      reactivation of cytomegalovirus, human herpesvirus 6 (HHV-6) and 7 (HHV-7). 
      Paired sera were collected from 22 patients with Bell's palsy and 24 patients 
      with sudden deafness. IgG antibody titres to HHV-7 were increased in one patient 
      with Bell's palsy. IgG antibody titres to HHV-6 were increased in one patient 
      with Bell's palsy and two with sudden deafness. IgG antibody titres to 
      cytomegalovirus were increased in one patient with sudden deafness. Titres of the 
      three viral antibodies were not increased simultaneously in any patients. These 
      viruses may contribute to the development of Bell's palsy or sudden deafness in 
      some cases. It is, however, unlikely that these viruses are the main cause of 
      Bell's palsy and sudden deafness in the majority of patients.
FAU - Takasaki, T
AU  - Takasaki T
AD  - Department of Microbiology, Kinki University School of Medicine, Osaka, Japan.
FAU - Higashikawa, M
AU  - Higashikawa M
FAU - Motoyama, S
AU  - Motoyama S
FAU - Sugita, K
AU  - Sugita K
FAU - Kurane, I
AU  - Kurane I
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Laryngol Otol
JT  - The Journal of laryngology and otology
JID - 8706896
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Antibodies, Viral/*blood
MH  - Cytomegalovirus/immunology
MH  - *Facial Nerve
MH  - Facial Paralysis/*virology
MH  - Female
MH  - Hearing Loss, Sudden/*virology
MH  - Herpesviridae/*immunology
MH  - Herpesvirus 6, Human/immunology
MH  - Herpesvirus 7, Human/immunology
MH  - Humans
MH  - Immunoglobulin G/*blood
MH  - Male
MH  - Middle Aged
EDAT- 1998/10/17 00:00
MHDA- 1998/10/17 00:01
CRDT- 1998/10/17 00:00
PHST- 1998/10/17 00:00 [pubmed]
PHST- 1998/10/17 00:01 [medline]
PHST- 1998/10/17 00:00 [entrez]
AID - 10.1017/s0022215100141271 [doi]
PST - ppublish
SO  - J Laryngol Otol. 1998 Jul;112(7):617-21. doi: 10.1017/s0022215100141271.