PMID- 9783698
OWN - NLM
STAT- MEDLINE
DCOM- 19981210
LR  - 20190831
IS  - 0146-6615 (Print)
IS  - 0146-6615 (Linking)
VI  - 56
IP  - 3
DP  - 1998 Nov
TI  - Detection of human herpesvirus 7 (HHV-7) DNA in breast milk by polymerase chain 
      reaction and prevalence of HHV-7 antibody in breast-fed and bottle-fed children.
PG  - 275-9
AB  - Twenty-nine breast milk mononuclear cell samples were analyzed for human 
      herpesvirus 7 (HHV-7) DNA, human herpesvirus 6 (HHV-6) DNA, and human 
      cytomegalovirus (HCMV) DNA by polymerase chain reaction (PCR). In addition, 
      peripheral blood mononuclear cell samples from 13 puerperants were analyzed for 
      HHV-7 DNA by PCR, and seropositivity of HHV-7 was also analyzed in breast-fed and 
      bottle-fed children. HHV-7 DNA was detected in 3 of 29 breast milk samples. HCMV 
      DNA was also detected in 3 of 29 breast milk samples, but HHV-6 DNA was not 
      detected. HHV-7 DNA was detected in 11 of 13 samples of peripheral blood 
      mononuclear cells. Though the seropositivity rate for HHV-7 in breast-fed 
      children was slightly higher than that in bottle-fed children at 18 and 24 months 
      old, the difference was not statistically significant. From these results, we 
      speculate that breast-feeding may be one of the transmission routes of HHV-7, 
      although this is not the main route.
FAU - Fujisaki, H
AU  - Fujisaki H
AD  - Department of Pediatrics, Faculty of Medicine, Osaka University, Suita, Japan.
FAU - Tanaka-Taya, K
AU  - Tanaka-Taya K
FAU - Tanabe, H
AU  - Tanabe H
FAU - Hara, T
AU  - Hara T
FAU - Miyoshi, H
AU  - Miyoshi H
FAU - Okada, S
AU  - Okada S
FAU - Yamanishi, K
AU  - Yamanishi K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Med Virol
JT  - Journal of medical virology
JID - 7705876
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Antibodies, Viral/*blood
MH  - Bottle Feeding
MH  - *Breast Feeding
MH  - Child, Preschool
MH  - Female
MH  - Fluorescent Antibody Technique, Indirect
MH  - Herpesviridae Infections/epidemiology/*transmission
MH  - Herpesvirus 7, Human/genetics/*immunology/*isolation & purification
MH  - Humans
MH  - Infant
MH  - Infectious Disease Transmission, Vertical
MH  - Leukocytes, Mononuclear/virology
MH  - Milk, Human/*virology
MH  - Polymerase Chain Reaction
MH  - Postpartum Period
MH  - Seroepidemiologic Studies
EDAT- 1998/10/23 02:01
MHDA- 2000/06/20 09:00
CRDT- 1998/10/23 02:01
PHST- 1998/10/23 02:01 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1998/10/23 02:01 [entrez]
AID - 10.1002/(SICI)1096-9071(199811)56:3<275::AID-JMV17>3.0.CO;2-D [pii]
AID - 10.1002/(sici)1096-9071(199811)56:3<275::aid-jmv17>3.0.co;2-d [doi]
PST - ppublish
SO  - J Med Virol. 1998 Nov;56(3):275-9. doi: 
      10.1002/(sici)1096-9071(199811)56:3<275::aid-jmv17>3.0.co;2-d.