PMID- 9787332 OWN - NLM STAT- MEDLINE DCOM- 19981110 LR - 20190915 IS - 1077-4114 (Print) IS - 1077-4114 (Linking) VI - 20 IP - 5 DP - 1998 Sep-Oct TI - Felty syndrome complicating juvenile rheumatoid arthritis. PG - 511-3 AB - PURPOSE: To describe a case of Felty syndrome (FS) in a child with (JRA) and review the previous literature on this rare entity. METHODS: Review of clinical data including results of serial blood counts, bone marrow aspirate, human leukocyte antigen (HLA)-typing, and abdominal sonography. RESULTS: Serial blood counts over 2 years revealed persistent leukopenia and thrombocytopenia. Bone marrow aspirate showed normal trilineage hematopoiesis, abdominal sonography demonstrated an enlarged spleen, but normal liver and portal circulation. HLA-typing was most significant for positivity of the DR 1 allele. CONCLUSION: This is only the third child, and the first preadolescent, to be reported with FS complicating juvenile rheumatoid arthritis. This condition needs to be considered in the differential diagnosis when leukopenia, thrombocytopenia, or both develop in patients with JRA. FAU - Bloom, B J AU - Bloom BJ AD - Department of Pediatrics, Hasbro Children's Hospital, Providence, Rhode Island 02903, USA. FAU - Smith, P AU - Smith P FAU - Alario, A J AU - Alario AJ LA - eng PT - Case Reports PT - Journal Article PL - United States TA - J Pediatr Hematol Oncol JT - Journal of pediatric hematology/oncology JID - 9505928 SB - IM MH - *Arthritis, Juvenile MH - Child, Preschool MH - *Felty Syndrome MH - Female MH - Humans EDAT- 1998/10/27 00:00 MHDA- 1998/10/27 00:01 CRDT- 1998/10/27 00:00 PHST- 1998/10/27 00:00 [pubmed] PHST- 1998/10/27 00:01 [medline] PHST- 1998/10/27 00:00 [entrez] AID - 10.1097/00043426-199809000-00022 [doi] PST - ppublish SO - J Pediatr Hematol Oncol. 1998 Sep-Oct;20(5):511-3. doi: 10.1097/00043426-199809000-00022.