PMID- 9789329
OWN - NLM
STAT- MEDLINE
DCOM- 19990308
LR  - 20220318
IS  - 0962-8924 (Print)
IS  - 0962-8924 (Linking)
VI  - 8
IP  - 10
DP  - 1998 Oct
TI  - Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.
PG  - 404-10
AB  - A number of developmental processes that involve cell migration, growth or 
      morphogenesis depend on extracellular signals. A molecule that provides such 
      signals, known as hepatocyte growth factor/scatter factor (HGF/SF), has attracted 
      considerable interest in recent years because of its distinct structure, 
      mechanism of activation and important roles throughout embryogenesis. This review 
      discusses the main features of HGF/SF and its receptor, the product of the c-met 
      protooncogene, and their role in embryogenesis.
FAU - Birchmeier, C
AU  - Birchmeier C
AD  - Dept of Medical Genetics, Max-Delbruck-Centrum for Molecular Medicine, Berlin, 
      Germany. cbirch@mdc-berlin.de
FAU - Gherardi, E
AU  - Gherardi E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Trends Cell Biol
JT  - Trends in cell biology
JID - 9200566
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Heparan Sulfate Proteoglycans)
RN  - 0 (PAX3 Transcription Factor)
RN  - 0 (PAX3 protein, human)
RN  - 0 (Paired Box Transcription Factors)
RN  - 0 (Transcription Factors)
RN  - 138016-91-8 (Pax3 protein, mouse)
RN  - 67256-21-7 (Hepatocyte Growth Factor)
RN  - EC 2.7.10.1 (Proto-Oncogene Proteins c-met)
SB  - IM
MH  - Animals
MH  - Cell Movement
MH  - Congenital Abnormalities/genetics
MH  - DNA-Binding Proteins/genetics/physiology
MH  - Embryonic and Fetal Development/genetics/*physiology
MH  - Epithelial Cells/cytology/drug effects
MH  - Heparan Sulfate Proteoglycans/metabolism
MH  - Hepatocyte Growth Factor/chemistry/*physiology
MH  - Humans
MH  - Liver/embryology
MH  - Mesoderm/metabolism
MH  - Mice
MH  - Mice, Knockout
MH  - Models, Molecular
MH  - Morphogenesis/physiology
MH  - Muscles/embryology
MH  - Nervous System/embryology
MH  - Neurons/physiology
MH  - PAX3 Transcription Factor
MH  - Paired Box Transcription Factors
MH  - Protein Conformation
MH  - Proto-Oncogene Proteins c-met/genetics/*physiology
MH  - Proto-Oncogenes
MH  - Signal Transduction
MH  - *Transcription Factors
RF  - 60
EDAT- 1998/10/28 00:00
MHDA- 1998/10/28 00:01
CRDT- 1998/10/28 00:00
PHST- 1998/10/28 00:00 [pubmed]
PHST- 1998/10/28 00:01 [medline]
PHST- 1998/10/28 00:00 [entrez]
AID - S0962-8924(98)01359-2 [pii]
AID - 10.1016/s0962-8924(98)01359-2 [doi]
PST - ppublish
SO  - Trends Cell Biol. 1998 Oct;8(10):404-10. doi: 10.1016/s0962-8924(98)01359-2.