PMID- 9797776
OWN - NLM
STAT- MEDLINE
DCOM- 19981104
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 106
IP  - 2
DP  - 1998 Oct 15
TI  - Fluorescence in situ hybridization characterization of the chromosomal 
      breakpoints in a case with ins(17;3)(q11.2;q21q26.3) and acute monocytic 
      leukemia.
PG  - 122-7
AB  - A 63-year-old patient with acute myeloid leukemia of FAB M5 subtype revealing 
      chromosomal breakpoints in 3q21 and 3q26 is presented. Although rearrangements of 
      3q21 and 3q26 are relatively common in patients with myelocytic malignancies, 
      this is the first report of ins(17;3)(q11.2;q21q26.3). We defined the chromosomal 
      breakpoints and the extent of the insertion by fluorescence in situ hybridization 
      (FISH) with yeast artificial chromosomes (YACs).
FAU - Schnittger, S
AU  - Schnittger S
AD  - AG Tumorcytogenetik, Institut fur Humangenetik der Medizinischen Universitat zu 
      Lubeck, Germany.
FAU - Joachimmayer, E
AU  - Joachimmayer E
FAU - Schoch, C
AU  - Schoch C
FAU - Fuchs, R
AU  - Fuchs R
FAU - Fonatsch, C
AU  - Fonatsch C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - *Chromosome Aberrations
MH  - *Chromosome Breakage
MH  - *Chromosomes, Human, Pair 17
MH  - *Chromosomes, Human, Pair 3
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leukemia, Monocytic, Acute/*genetics
MH  - Middle Aged
MH  - Reverse Transcriptase Polymerase Chain Reaction
EDAT- 1998/11/03 00:00
MHDA- 1998/11/03 00:01
CRDT- 1998/11/03 00:00
PHST- 1998/11/03 00:00 [pubmed]
PHST- 1998/11/03 00:01 [medline]
PHST- 1998/11/03 00:00 [entrez]
AID - S0165460898000715 [pii]
AID - 10.1016/s0165-4608(98)00071-5 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1998 Oct 15;106(2):122-7. doi: 
      10.1016/s0165-4608(98)00071-5.