PMID- 9799611 OWN - NLM STAT- MEDLINE DCOM- 19981231 LR - 20211203 IS - 0888-7543 (Print) IS - 0888-7543 (Linking) VI - 53 IP - 3 DP - 1998 Nov 1 TI - Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter. PG - 406-9 AB - This report describes the identification of a cDNA encoding STK13, a third human protein kinase related to the Drosophila Aurora and the budding yeast Ipl1 kinases. After screening of a human placental cDNA library with a Xenopus laevis cDNA encoding the pEg2 protein kinase and 5' RACE on testis mRNA, a full-length cDNA was isolated. The chromosomal localization of STK13 on 19q13.3-ter between the markers D19S210 and D19S218 was established by a combination of somatic cell and radiation hybrid panel PCR screening. The localization of STK13 on human chromosome 19 was confirmed by fluorescence in situ hybridization (FISH) using a genomic clone containing STK13 as a probe. CI - Copyright 1998 Academic Press. FAU - Bernard, M AU - Bernard M AD - Departement de Biologie et Genetique du Developpement, Groupe Cycle Cellulaire, CNRS UPR 41, Rennes Cedex, 35042, France. FAU - Sanseau, P AU - Sanseau P FAU - Henry, C AU - Henry C FAU - Couturier, A AU - Couturier A FAU - Prigent, C AU - Prigent C LA - eng SI - GDB/9837399 SI - GENBANK/AF059681 SI - GENBANK/AF059682 PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Genomics JT - Genomics JID - 8800135 RN - 0 (DNA Primers) RN - 0 (DNA, Complementary) RN - 0 (Intracellular Signaling Peptides and Proteins) RN - 0 (Saccharomyces cerevisiae Proteins) RN - EC 2.7.- (Protein Kinases) RN - EC 2.7.11.1 (AURKC protein, human) RN - EC 2.7.11.1 (Aurora Kinase C) RN - EC 2.7.11.1 (Aurora Kinases) RN - EC 2.7.11.1 (IPL1 protein, S cerevisiae) RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases) SB - IM MH - Amino Acid Sequence MH - Animals MH - Aurora Kinase C MH - Aurora Kinases MH - Base Sequence MH - Chromosome Mapping MH - Chromosomes, Human, Pair 19/*genetics MH - Cloning, Molecular MH - DNA Primers/genetics MH - DNA, Complementary/genetics/isolation & purification MH - Drosophila/genetics MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Intracellular Signaling Peptides and Proteins MH - Male MH - Molecular Sequence Data MH - Pregnancy MH - Protein Kinases/*genetics MH - Protein Serine-Threonine Kinases/*genetics MH - Saccharomyces cerevisiae/genetics MH - *Saccharomyces cerevisiae Proteins MH - Xenopus laevis/genetics EDAT- 1998/11/04 00:00 MHDA- 1998/11/04 00:01 CRDT- 1998/11/04 00:00 PHST- 1998/11/04 00:00 [pubmed] PHST- 1998/11/04 00:01 [medline] PHST- 1998/11/04 00:00 [entrez] AID - S0888-7543(98)95522-7 [pii] AID - 10.1006/geno.1998.5522 [doi] PST - ppublish SO - Genomics. 1998 Nov 1;53(3):406-9. doi: 10.1006/geno.1998.5522.