PMID- 9804891
OWN - NLM
STAT- MEDLINE
DCOM- 19981223
LR  - 20190831
IS  - 0165-3806 (Print)
IS  - 0165-3806 (Linking)
VI  - 111
IP  - 1
DP  - 1998 Nov 1
TI  - Development of NADPH-diaphorase expression in chemosensory systems of the 
      opossum, Monodelphis domestica.
PG  - 51-63
AB  - Using NADPH-diaphorase histochemistry, the present study describes development of 
      olfactory and vomeronasal systems in postnatal opossums, Monodelphis domestica. 
      NADPH-dependent staining is absent at and around the time of birth. By 2 weeks of 
      age and through adulthood, intense staining is seen along the luminal surface of 
      the olfactory epithelium (OE) and of the vomeronasal sensory epithelium (VNE), as 
      well as in Bowman's glands of the OE. Staining of the adult VNE is not 
      homogeneous; it is restricted to the superficial 2/3 of the epithelium. At 2 
      weeks of age, staining in the brain is seen only at the surface of the ventricles 
      and in blood vessels. At 1 month of age and through adulthood, staining of 
      varying intensity is seen in individual olfactory bulb glomeruli, although the 
      incoming olfactory axons are relatively unstained. Interestingly, whereas at 30 
      days of age, staining of the accessory olfactory bulb (AOB) glomeruli is uniform, 
      2 weeks later and in the adult, NADPH staining is concentrated in the rostral 
      half, with little or no staining observed in the posterior portion. Darkly 
      stained periglomerular cells are seen throughout the extent of the 
      differentially-stained glomerular layer. From 30 days of age and through 
      adulthood, intense NADPH staining is also observed in the islands of Calleja, as 
      well as in cells of the dorsal cortex, often associated with the path of the 
      rostral migratory stream.
CI  - Copyright 1998 Elsevier Science B.V.
FAU - Shapiro, L S
AU  - Shapiro LS
AD  - Program in Neural and Behavioral Sciences, Health Science Center at Brooklyn, 
      State University of New York, 450 Clarkson Avenue, Brooklyn, New York, NY 11203, 
      USA.
FAU - Halpern, M
AU  - Halpern M
LA  - eng
GR  - DC02745/DC/NIDCD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res Dev Brain Res
JT  - Brain research. Developmental brain research
JID - 8908639
RN  - EC 1.6.99.1 (NADPH Dehydrogenase)
SB  - IM
MH  - Aging/metabolism
MH  - Animals
MH  - Brain/enzymology
MH  - Chemoreceptor Cells/*metabolism
MH  - NADPH Dehydrogenase/*metabolism
MH  - Nasal Mucosa/enzymology
MH  - Olfactory Bulb/enzymology
MH  - Olfactory Nerve/enzymology
MH  - Olfactory Pathways/enzymology
MH  - Opossums/genetics/*metabolism
MH  - Vomeronasal Organ/enzymology
EDAT- 1998/11/07 00:00
MHDA- 1998/11/07 00:01
CRDT- 1998/11/07 00:00
PHST- 1998/11/07 00:00 [pubmed]
PHST- 1998/11/07 00:01 [medline]
PHST- 1998/11/07 00:00 [entrez]
AID - S0165380698001229 [pii]
AID - 10.1016/s0165-3806(98)00122-9 [doi]
PST - ppublish
SO  - Brain Res Dev Brain Res. 1998 Nov 1;111(1):51-63. doi: 
      10.1016/s0165-3806(98)00122-9.