PMID- 9805253
OWN - NLM
STAT- MEDLINE
DCOM- 19990119
LR  - 20190817
IS  - 0047-1828 (Print)
IS  - 0047-1828 (Linking)
VI  - 62
IP  - 10
DP  - 1998 Oct
TI  - Decreasing parasympathetic tone activity and proarrhythmic effect after 
      radiofrequency catheter ablation--differences in ablation site.
PG  - 733-40
AB  - Holter ECG was used to evaluate changes in heart rate variability (HRV), 
      indicators of the autonomic nervous system, and arrhythmia before and after 
      radiofrequency (RF) catheter ablation in patients with symptomatic 
      supraventricular tachycardia. Ablation targets in 43 patients included the 
      atrioventricular (AV) nodal pathway (AVNRT, n = 17), a right free wall accessory 
      pathway (n = 10), a septal accessory pathway (n = 6), and a left free wall 
      accessory pathway (n = 10). The High frequency component (0.15 - 0.40 Hz) or 
      pNN50 of HRV analysis, indicating parasympathetic activity, significantly 
      decreased immediately after RF ablation in the AVNRT and septal accessory pathway 
      groups, but not in the right or left wall groups. In contrast, in all four 
      groups, ventricular premature contractions (VPCs) significantly increased in most 
      of the patients, and ventricular tachycardia occurred in a few of the patients 
      immediately after RF ablation. There was no serious arrhythmia. These alterations 
      in HRV analysis and arrhythmia returned to the control level after 1 week or 
      more. VPCs after RF ablation did not consistently increase as a result of the 
      reduced parasympathetic tone activity, but at the lesion near the conduction 
      system, the increase in VPCs was inhibited by higher parasympathetic tone 
      activity, because the parasympathetic nerve fibers and receptors were distributed 
      in these lesions.
FAU - Jinbo, Y
AU  - Jinbo Y
AD  - Third Department of Internal Medicine, Showa University, School of Medicine, 
      Tokyo, Japan.
FAU - Kobayashi, Y
AU  - Kobayashi Y
FAU - Miyata, A
AU  - Miyata A
FAU - Chiyoda, K
AU  - Chiyoda K
FAU - Nakagawa, H
AU  - Nakagawa H
FAU - Tanno, K
AU  - Tanno K
FAU - Kurano, K
AU  - Kurano K
FAU - Kikushima, S
AU  - Kikushima S
FAU - Baba, T
AU  - Baba T
FAU - Katagiri, T
AU  - Katagiri T
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Jpn Circ J
JT  - Japanese circulation journal
JID - 7806868
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - *Catheter Ablation/adverse effects
MH  - Electrocardiography, Ambulatory
MH  - Heart Rate
MH  - Heart Ventricles/*innervation/pathology
MH  - Humans
MH  - Middle Aged
MH  - Parasympathetic Nervous System/*physiopathology
MH  - Tachycardia, Supraventricular/pathology/*therapy
EDAT- 1998/11/07 00:00
MHDA- 1998/11/07 00:01
CRDT- 1998/11/07 00:00
PHST- 1998/11/07 00:00 [pubmed]
PHST- 1998/11/07 00:01 [medline]
PHST- 1998/11/07 00:00 [entrez]
AID - 10.1253/jcj.62.733 [doi]
PST - ppublish
SO  - Jpn Circ J. 1998 Oct;62(10):733-40. doi: 10.1253/jcj.62.733.