PMID- 9812189
OWN - NLM
STAT- MEDLINE
DCOM- 19990114
LR  - 20191024
IS  - 0954-6928 (Print)
IS  - 0954-6928 (Linking)
VI  - 9
IP  - 6
DP  - 1998
TI  - Aortic valve replacement in patients older than 85 years: outcomes and the effect 
      on their quality of life.
PG  - 373-80
AB  - PURPOSE: The aim of this study was to investigate the outcome of aortic valve 
      replacement (AVR) and the effect on quality of life in patients aged over 85 who 
      had symptomatic aortic stenosis. METHODS: We performed a retrospective analysis 
      of 21 patients, aged 85-91 years (mean age 86.5), who underwent AVR, 10 of whom 
      underwent concomitant coronary artery bypass grafting (CABG) between 1989 and 
      1995. All patients were categorized as New York Heart Association (NYHA) 
      functional class III and IV. A questionnaire was used to evaluate heart symptoms 
      and quality of life among the 13 patients who were alive at follow-up (9-83 
      months). RESULTS: Eighteen patients were categorized as NYHA functional class I 
      and II for 1 year (9 months for one patient) after AVR. Three patients, all 
      undergoing concomitant CABG, died early. The overall 1-, 2- and 3-year actuarial 
      survival rate was 85%, 64% and 53% (among the patients undergoing only AVR the 
      figures were 100%, 100% and 85%). Follow-up questionnaire results showed an 
      improvement in the patients' symptoms of heart disease, dyspnea (P = 0.017) and 
      angina (P = 0.03). An improvement in the patients' physical functioning (P = 
      0.025), satisfaction with physical ability (P = 0.005), sleep (P = 0.025), health 
      status (P = 0.025) and perception of general health (P = 0.005) was also 
      observed. CONCLUSIONS: Our results show that AVR can be performed on patients > 
      or = 85 years of age or older, with an improvement in heart symptoms and quality 
      of life.
FAU - Levin, I L
AU  - Levin IL
AD  - Department of Cardiology, University Hospital of Lund, Sweden.
FAU - Olivecrona, G K
AU  - Olivecrona GK
FAU - Thulin, L I
AU  - Thulin LI
FAU - Olsson, S B
AU  - Olsson SB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Coron Artery Dis
JT  - Coronary artery disease
JID - 9011445
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve
MH  - Aortic Valve Stenosis/surgery
MH  - Bioprosthesis/statistics & numerical data
MH  - Coronary Artery Bypass/statistics & numerical data
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Prosthesis/statistics & numerical data
MH  - *Heart Valve Prosthesis Implantation/statistics & numerical data
MH  - Humans
MH  - Male
MH  - *Quality of Life
MH  - Retrospective Studies
MH  - Surveys and Questionnaires
MH  - Sweden
MH  - Treatment Outcome
EDAT- 1998/11/13 00:00
MHDA- 1998/11/13 00:01
CRDT- 1998/11/13 00:00
PHST- 1998/11/13 00:00 [pubmed]
PHST- 1998/11/13 00:01 [medline]
PHST- 1998/11/13 00:00 [entrez]
AID - 10.1097/00019501-199809060-00009 [doi]
PST - ppublish
SO  - Coron Artery Dis. 1998;9(6):373-80. doi: 10.1097/00019501-199809060-00009.