PMID- 9817590
OWN - NLM
STAT- MEDLINE
DCOM- 19990129
LR  - 20190712
IS  - 0031-9384 (Print)
IS  - 0031-9384 (Linking)
VI  - 64
IP  - 5
DP  - 1998 Jul
TI  - Firing properties of olfactory bulb neurons during sniffing in rats.
PG  - 755-64
AB  - Single unit activities from the olfactory bulb were recorded during sniffing in 
      unanesthetized rats. Spectral analyses by the Walsh transform were applied to the 
      spike trains of units. In addition, inter-spike intervals (ISIs) were measured to 
      estimate post-spike excitability and serial correlations. The modulation of 
      firing due to respiration cycles was observed only in four units (10%). 
      Thirty-three units (82.5%) displayed low-frequency fluctuations such as 1/f noise 
      in spike density. Their spectral density for the low-frequency range was 
      inversely proportional to the frequency, to the power of 0.08-0.55. These units 
      also showed "hyper-recovery" in post-spike excitability. In addition, the 
      first-order serial correlation of ISIs was significantly positive in 36 units 
      (90%). The degree of 1/f fluctuation was significantly correlated with the 
      amplitude of "hyper-recovery" in post-spike excitability and with the serial 
      correlation coefficient. To test the hypothesis that the self-facilitation of a 
      neuron causes 1/f fluctuations in its spike trains, simulations of single neuron 
      activity with self-facilitation were performed using an integrate-and-fire neuron 
      model, and its spike trains were analyzed. The model neuron with 
      self-facilitation mimicked the characteristics observed in olfactory bulb neurons 
      such as 1/f fluctuations in spike density, positive correlations between 
      successive ISIs and "hyper-recovery" in post-spike excitability. These results 
      suggest that olfactory bulb neurons have a mechanism for self-facilitation 
      causing 1/f fluctuations in spike density.
FAU - Ogawa, Y
AU  - Ogawa Y
AD  - Department of Physiology, Nara Medical University, Kashihara, Japan. 
      yogawa@naramed-u.ac.jp
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
SB  - IM
MH  - Algorithms
MH  - Animals
MH  - Behavior, Animal/*physiology
MH  - Electric Stimulation
MH  - Electroencephalography
MH  - Male
MH  - Neurons/*physiology
MH  - Olfactory Bulb/anatomy & histology/cytology/*physiology
MH  - Rats
MH  - Rats, Wistar
MH  - Smell/*physiology
EDAT- 1998/11/17 00:00
MHDA- 1998/11/17 00:01
CRDT- 1998/11/17 00:00
PHST- 1998/11/17 00:00 [pubmed]
PHST- 1998/11/17 00:01 [medline]
PHST- 1998/11/17 00:00 [entrez]
AID - S0031938498001371 [pii]
AID - 10.1016/s0031-9384(98)00137-1 [doi]
PST - ppublish
SO  - Physiol Behav. 1998 Jul;64(5):755-64. doi: 10.1016/s0031-9384(98)00137-1.