PMID- 9827936
OWN - NLM
STAT- MEDLINE
DCOM- 19981229
LR  - 20190705
IS  - 0007-1048 (Print)
IS  - 0007-1048 (Linking)
VI  - 103
IP  - 2
DP  - 1998 Nov
TI  - Successful adoptive immunotherapy for relapse of AML 9 years after 
      T-cell-depleted BMT.
PG  - 563-4
AB  - Relapse is one of the main problems which can occur following allogeneic 
      transplantation for haematological malignancies. In this situation the 
      enhancement of the graft-versus-leukaemia effect by transfusion of donor buffy 
      coats with or without cytokines may lead to complete remission especially in 
      myeloid leukaemias. FISH (fluorescence in situ hybridization) is a sensitive 
      method to monitor chimaerism in gender-different transplantation. We report a 
      case of successful buffy coat transfer therapy > 9 years after bone marrow 
      transplantation. This is the longest interval reported, to our knowledge, between 
      transplantation to relapse, which was treated by adoptive immunotherapy. Complete 
      donor chimaerism was confirmed by FISH.
FAU - Bertz, H
AU  - Bertz H
AD  - Albert Ludwigs University Medical Centre, Department of Haematology/Oncology, 
      Freiburg, Germany.
FAU - Kunzman, R
AU  - Kunzman R
FAU - Bunjes, D
AU  - Bunjes D
FAU - Finke, J
AU  - Finke J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Br J Haematol
JT  - British journal of haematology
JID - 0372544
SB  - IM
MH  - Adult
MH  - *Bone Marrow Transplantation
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - *Immunotherapy, Adoptive
MH  - Leukemia, Myeloid, Acute/*therapy
MH  - *Lymphocyte Depletion
MH  - *Lymphocyte Transfusion
MH  - Recurrence
MH  - T-Lymphocytes
EDAT- 1998/11/25 00:00
MHDA- 1998/11/25 00:01
CRDT- 1998/11/25 00:00
PHST- 1998/11/25 00:00 [pubmed]
PHST- 1998/11/25 00:01 [medline]
PHST- 1998/11/25 00:00 [entrez]
AID - 10.1046/j.1365-2141.1998.01007.x [doi]
PST - ppublish
SO  - Br J Haematol. 1998 Nov;103(2):563-4. doi: 10.1046/j.1365-2141.1998.01007.x.