PMID- 9829795
OWN - NLM
STAT- MEDLINE
DCOM- 19990126
LR  - 20190909
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 112
IP  - 5
DP  - 1998 Oct
TI  - Functional connections between medial prefrontal cortex and caudate-putamen in 
      brain-stimulation reward of rats.
PG  - 1177-86
AB  - Rats were trained to self-stimulate for trains of cathodal pulses delivered via 
      electrodes placed in the medial prefrontal cortex (MPFC) and caudate-putamen 
      (CPu). When the pulses were delivered via 9 ipsilateral MPFC and CPu sites 
      alternately, summation varied from 13% to 40%. However, the overall summation for 
      2 contralateral MPFC-CPu pairs was 5%, thus indicating a greater integration of 
      ipsilateral than contralateral reward signals. When the interval between 
      alternate pulses decreased in 4 of the 9 ipsilateral pairs, the summation also 
      decreased, an outcome consistent with collision of action potentials passing 
      between the MPFC and CPu sites. The size of the collision effect ranged from 15% 
      to 33%. Estimates of conduction velocity varied between 0.4 to 5.4 m/s, with a 
      1.7 m/s average. According to these values, the neurons connecting the MPFC and 
      CPu self-stimulation sites appear to be slower than the ones that have been shown 
      to link reward fibers that course between posterior brain regions.
FAU - Trzcinska, M
AU  - Trzcinska M
AD  - School of Psychology, University of Ottawa, Ontario, Canada. monikat@bu.edu
FAU - Bielajew, C
AU  - Bielajew C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
SB  - IM
MH  - Animals
MH  - Caudate Nucleus/cytology/*physiology
MH  - Conditioning, Operant
MH  - Electric Stimulation/methods
MH  - Electrodes, Implanted
MH  - Male
MH  - Nerve Net
MH  - Neural Conduction/physiology
MH  - Prefrontal Cortex/cytology/*physiology
MH  - Putamen/cytology/*physiology
MH  - Rats
MH  - Rats, Long-Evans
MH  - Reaction Time
MH  - Self Stimulation/*physiology
EDAT- 1998/11/26 00:00
MHDA- 1998/11/26 00:01
CRDT- 1998/11/26 00:00
PHST- 1998/11/26 00:00 [pubmed]
PHST- 1998/11/26 00:01 [medline]
PHST- 1998/11/26 00:00 [entrez]
AID - 10.1037//0735-7044.112.5.1177 [doi]
PST - ppublish
SO  - Behav Neurosci. 1998 Oct;112(5):1177-86. doi: 10.1037//0735-7044.112.5.1177.