PMID- 9867155 OWN - NLM STAT- MEDLINE DCOM- 19990114 LR - 20161124 IS - 0161-5505 (Print) IS - 0161-5505 (Linking) VI - 39 IP - 12 DP - 1998 Dec TI - Technetium-99m(V)-DMSA and gallium-67 in the assessment of bone and joint infection. PG - 2128-31 AB - The aim of our study was to investigate the diagnostic value of scans with 99mTc(V)-dimercaptosuccinic acid (DMSA) to localize bone and joint infection compared with scans using 67Ga. METHODS: Thirty-six patients referred for investigation of bone and joint infection were studied. In all patients, a bone scan was obtained initially. Subsequently, comparative scans with 99mTc(V)-DMSA and 67Ga were performed 1 wk apart. Microbiological findings, pathologic findings and/or clinical follow-up (until symptoms disappeared) were considered to be proof of the presence of bone and joint infection. RESULTS: Technetium-99m (V)-DMSA showed greater sensitivity and accuracy than 67Ga in the assessment of bone and joint infection, although the difference was not statistically significant. CONCLUSION: In comparison with a 67Ga scan, a 99mTc(V)-DMSA scan, in combination with a bone scan, is a reliable way to diagnose bone and joint infection. Both tracers were useful in the diagnosis of bone and joint infection. FAU - Lee, B F AU - Lee BF AD - Department of Nuclear Medicine, Institute of Medicine, Kaohsiung Medical College Hospital, Taiwan. FAU - Chiu, N T AU - Chiu NT FAU - Chang, J K AU - Chang JK FAU - Liu, G C AU - Liu GC FAU - Yu, H S AU - Yu HS LA - eng PT - Journal Article PL - United States TA - J Nucl Med JT - Journal of nuclear medicine : official publication, Society of Nuclear Medicine JID - 0217410 RN - 0 (Gallium Radioisotopes) RN - 0 (Radiopharmaceuticals) RN - 494JNQ8L28 (Technetium Tc 99m Dimercaptosuccinic Acid) SB - IM MH - Adult MH - Aged MH - Bone Diseases, Infectious/*diagnostic imaging MH - Child MH - Child, Preschool MH - Communicable Diseases/*diagnostic imaging MH - False Negative Reactions MH - False Positive Reactions MH - Female MH - *Gallium Radioisotopes MH - Humans MH - Joint Diseases/*diagnostic imaging MH - Male MH - Middle Aged MH - Radionuclide Imaging MH - *Radiopharmaceuticals MH - Reproducibility of Results MH - Retrospective Studies MH - Sensitivity and Specificity MH - *Technetium Tc 99m Dimercaptosuccinic Acid EDAT- 1998/12/29 00:00 MHDA- 1998/12/29 00:01 CRDT- 1998/12/29 00:00 PHST- 1998/12/29 00:00 [pubmed] PHST- 1998/12/29 00:01 [medline] PHST- 1998/12/29 00:00 [entrez] PST - ppublish SO - J Nucl Med. 1998 Dec;39(12):2128-31.