PMID- 9867178
OWN - NLM
STAT- MEDLINE
DCOM- 19990211
LR  - 20190905
IS  - 0364-2348 (Print)
IS  - 0364-2348 (Linking)
VI  - 27
IP  - 11
DP  - 1998 Nov
TI  - Use of contrast-enhanced MR imaging to detect sacroiliitis in children.
PG  - 606-16
AB  - PURPOSE: To verify the diagnostic value of contrast-enhanced MR imaging compared 
      with conventional radiography in the diagnosis of sacroiliitis in children. 
      DESIGN AND PATIENTS: Radiography and MR imaging of the sacroiliac joints were 
      performed in 185 children subdivided into the following groups according to the 
      modified European Spondyloarthropathy (SpA) Study Group (ESSG) criteria: group 1, 
      undifferentiated spondyloarthropathy (uSpA) (n=53, 94.5% HLA-B27+); group 2, 
      differentiated SpA (n=45, 93.3% HLA-B27+); group 3, patients with no signs of SpA 
      other than oligoarthritis (n=39, 92.3% HLA-B27+); group 4, HLA-B27+ controls with 
      various other non-SpA diagnoses (n=22); and group 5, HLA-B27-controls with 
      various other non-SpA diagnoses (n=26). Radiographs were evaluated on the basis 
      of the modified New York criteria independently by three experienced radiologists 
      masked to the clinical data. In a second step, the same radiologists 
      independently evaluated the MR images without knowledge of the clinical data and 
      radiographic findings using the recently published criteria developed by our 
      group. These criteria allow differentiation of acute and chronic inflammatory 
      changes. RESULTS: Radiography demonstrated sacroiliitis in 18 patients: 4 of 53 
      in group 1 (7.5%), 14 of 45 in group 2 (31%), but none in groups 3, 4 and 5. In 
      contrast, MR imaging demonstrated acute and/or chronic sacroiliitis in 44 
      patients: 18 of 53 in group 1 (34%), 21 of 45 in group 2 (46.7%) and 5 of 39 in 
      group 3 (12.8%), but none in groups 4 and 5. The percentage of sacroiliitis 
      detected by MR imaging was significantly higher than that detected by radiography 
      (P<0.001). CONCLUSION: Contrast-enhanced MR imaging is a useful method for 
      detecting sacroiliitis in children. Advantages of contrast-enhanced MR imaging 
      compared with conventional radiography are a higher sensitivity due to the 
      ability to document early and acute changes and the absence of radiation 
      exposure.
FAU - Bollow, M
AU  - Bollow M
AD  - Department of Radiology, Charite Campus Mitte, Humboldt-Universitat zu Berlin, 
      Germany.
FAU - Braun, J
AU  - Braun J
FAU - Biedermann, T
AU  - Biedermann T
FAU - Mutze, S
AU  - Mutze S
FAU - Paris, S
AU  - Paris S
FAU - Schauer-Petrowskaja, C
AU  - Schauer-Petrowskaja C
FAU - Minden, K
AU  - Minden K
FAU - Schmitz, S A
AU  - Schmitz SA
FAU - Schontube, M
AU  - Schontube M
FAU - Hamm, B
AU  - Hamm B
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Germany
TA  - Skeletal Radiol
JT  - Skeletal radiology
JID - 7701953
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adolescent
MH  - Arthritis/*diagnosis
MH  - Arthritis, Psoriatic/diagnosis
MH  - Arthritis, Reactive/diagnosis
MH  - Child
MH  - *Contrast Media
MH  - Female
MH  - *Gadolinium DTPA
MH  - Humans
MH  - Magnetic Resonance Imaging/instrumentation/*methods/statistics & numerical data
MH  - Male
MH  - Prospective Studies
MH  - Radiography
MH  - Sacroiliac Joint/diagnostic imaging/*pathology
MH  - Sensitivity and Specificity
MH  - Spondylitis, Ankylosing/diagnosis
MH  - Statistics, Nonparametric
EDAT- 1998/12/29 00:00
MHDA- 1998/12/29 00:01
CRDT- 1998/12/29 00:00
PHST- 1998/12/29 00:00 [pubmed]
PHST- 1998/12/29 00:01 [medline]
PHST- 1998/12/29 00:00 [entrez]
AID - 10.1007/s002560050446 [doi]
PST - ppublish
SO  - Skeletal Radiol. 1998 Nov;27(11):606-16. doi: 10.1007/s002560050446.