PMID- 9882557
OWN - NLM
STAT- MEDLINE
DCOM- 19990322
LR  - 20081121
IS  - 0026-2862 (Print)
IS  - 0026-2862 (Linking)
VI  - 57
IP  - 1
DP  - 1999 Jan
TI  - Is there any relationship between cold-induced vasodilatation and vasomotion?
PG  - 1-7
AB  - There are many analogies between cold-induced vasodilatation (CIV) and vasomotion 
      (VM), but the demonstration of any relationship between these two microvascular 
      homeostatic reactions is to date lacking. In a group of seven controls and seven 
      patients with Raynaud phenomenon in the vasomotor stage of the disease, we 
      studied, by means of laser Doppler fluxmetry, the fingertip flow at room 
      temperature (15 min), during hand immersion into cold water (0-6 degreesC, 30 
      min), and at room temperature again (15 min). The Fourier spectral analysis of 
      the laser Doppler signal revealed in both groups two different patterns of the 
      fingertip flow oscillations: the first was characterized by continued 
      oscillations with small amplitude and median frequency of 2-8 cycles/min 
      occurring both at room temperature and during cold stimulation. The second was 
      characterized by continued oscillations of high amplitude and median frequency of 
      1 cycle/4-6 min occurring during cold stimulation only. The first pattern of flow 
      oscillations still occurred during the second. The high-frequency oscillations 
      are similar to the waves of vasomotion and the low-frequency oscillations are 
      similar to the waves of cold-induced vasodilatation. Because 90-98% of the 
      fingertip flow passes through arteriolar-venular anastomosis (AVAs), our results 
      suggest that the CIV flow oscillations may be an expression of the AVA's VM.
CI  - Copyright 1999 Academic Press.
FAU - Nuzzaci, G
AU  - Nuzzaci G
AD  - Clinical Medicine and Cardiology Institute, Department of Systems and Computer 
      Sciences, University of Florence, Viale Morgagni, Florence, 85-50134, Italy.
FAU - Evangelisti, A
AU  - Evangelisti A
FAU - Righi, D
AU  - Righi D
FAU - Giannico, G
AU  - Giannico G
FAU - Nuzzaci, I
AU  - Nuzzaci I
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Microvasc Res
JT  - Microvascular research
JID - 0165035
SB  - IM
MH  - Adult
MH  - Arteriovenous Anastomosis/physiology
MH  - *Cold Temperature
MH  - Female
MH  - Fingers/blood supply
MH  - Fourier Analysis
MH  - Humans
MH  - Immersion
MH  - Laser-Doppler Flowmetry
MH  - Male
MH  - Muscle, Smooth, Vascular/*physiology
MH  - Periodicity
MH  - Raynaud Disease/*physiopathology
MH  - Vasodilation/*physiology
MH  - Vasomotor System/physiology
EDAT- 1999/01/12 00:00
MHDA- 1999/01/12 00:01
CRDT- 1999/01/12 00:00
PHST- 1999/01/12 00:00 [pubmed]
PHST- 1999/01/12 00:01 [medline]
PHST- 1999/01/12 00:00 [entrez]
AID - S0026-2862(98)92114-8 [pii]
AID - 10.1006/mvre.1998.2114 [doi]
PST - ppublish
SO  - Microvasc Res. 1999 Jan;57(1):1-7. doi: 10.1006/mvre.1998.2114.