PMID- 9884707 OWN - NLM STAT- MEDLINE DCOM- 19990125 LR - 20181201 IS - 0507-3758 (Print) IS - 0507-3758 (Linking) VI - 44 IP - 5 DP - 1998 TI - [Clinical evaluation of the effectiveness of radiotherapy in vaginal metastases of uterine cancer]. PG - 522-5 AB - The data on 132 patients with metastases of endometrial carcinoma into the vagina (MECV) were analysed. Among the modalities used were complex (remote + contact) and contact radiotherapy with low-, medium- and high dosage. The following radiobiological models were employed to assess tissue response: time-dose-fractionation factor, cumulative radiation effect and linear-quadratic dose effect equation ("extrapolated dose of response"). There was a correlation between five-year survival in radiation-treated patients and metastasis size. Stage of disease proved a major prognostic factor in MECV treatment. Complex radiotherapy was of crucial importance in MECV treatment whatever the size of disseminated tumor. There was no correlation between efficacy of MECV treatment and therapy used to treat primary endometrial carcinoma (surgery, combined or radiotherapy). FAU - Kanaev, S V AU - Kanaev SV AD - Prof. N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF, St. Petersburg. FAU - Turkevich, V G AU - Turkevich VG LA - rus PT - Comparative Study PT - Journal Article TT - Klinicheskaia otsenka effektivnosti luchevogo lecheniia metastazov raka tela matki vo vlagalishche. PL - Russia (Federation) TA - Vopr Onkol JT - Voprosy onkologii JID - 0413775 SB - IM MH - Brachytherapy MH - Combined Modality Therapy MH - Data Interpretation, Statistical MH - Dose Fractionation, Radiation MH - Evaluation Studies as Topic MH - Female MH - Follow-Up Studies MH - Humans MH - Lymphatic Metastasis MH - Radiotherapy Dosage MH - Time Factors MH - *Uterine Neoplasms/mortality MH - Vaginal Neoplasms/mortality/*radiotherapy/secondary/surgery EDAT- 1999/01/13 00:00 MHDA- 1999/01/13 00:01 CRDT- 1999/01/13 00:00 PHST- 1999/01/13 00:00 [pubmed] PHST- 1999/01/13 00:01 [medline] PHST- 1999/01/13 00:00 [entrez] PST - ppublish SO - Vopr Onkol. 1998;44(5):522-5.