PMID- 988942
OWN - NLM
STAT- MEDLINE
DCOM- 19761001
LR  - 20191028
IS  - 0001-5148 (Print)
IS  - 0001-5148 (Linking)
VI  - 31
IP  - 3
DP  - 1976 Jun
TI  - An electron microscope study of receptor site on rat mast cells for human 
      immunoglobulin E.
PG  - 184-92
AB  - Previous studies using immunofluorescence and autoradiography demonstrated the 
      presence of specific immunoglobulin E (IgE) receptors on rat mast cells (RMC). 
      This finding was confirmed by the use of transmission electron microscopy (TEM) 
      combined with X-ray microanalysis (XMA) employing ferritin labelled antisera XMA 
      was used to detect ferritin as Fe in the target cells. On examination by TEM and 
      XMA, 25 per cent of RMC showed a dense area of Fe deposits on the surface of the 
      cells. No Fe could be detected on neutrophils or eosinophils or in the control 
      cell preparations without human IgE. The Fe was concentrated in well-defined 
      areas of the treated mast cells and this distinct concentration of receptor sites 
      was similar to that observed by other investigators who have termed this 
      phenomenon, "cap" formation.
FAU - Pontefract, R
AU  - Pontefract R
FAU - Perelmutter, L
AU  - Perelmutter L
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - Acta Allergol
JT  - Acta allergologica
JID - 0370567
RN  - 0 (Immune Sera)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 9007-73-2 (Ferritins)
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - Animals
MH  - *Binding Sites, Antibody
MH  - Ferritins/immunology
MH  - Immune Sera
MH  - *Immunoglobulin E
MH  - Iron/immunology
MH  - Mast Cells/immunology/*ultrastructure
MH  - Rats
EDAT- 1976/06/01 00:00
MHDA- 1976/06/01 00:01
CRDT- 1976/06/01 00:00
PHST- 1976/06/01 00:00 [pubmed]
PHST- 1976/06/01 00:01 [medline]
PHST- 1976/06/01 00:00 [entrez]
AID - 10.1111/j.1398-9995.1976.tb01679.x [doi]
PST - ppublish
SO  - Acta Allergol. 1976 Jun;31(3):184-92. doi: 10.1111/j.1398-9995.1976.tb01679.x.