PMID- 9930435
OWN - NLM
STAT- MEDLINE
DCOM- 19990218
LR  - 20190628
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 66
IP  - 6 Suppl
DP  - 1998 Dec
TI  - Early calcific stenosis of the aortic sorin pericarbon valve implanted in the 
      elderly.
PG  - S139-42
AB  - BACKGROUND: We reviewed our experience with the Sorin Pericarbon (Sorin, 
      Saluggia, Italy) valve implanted in the aortic position. METHODS: From January 
      1990 to January 1996, 143 consecutive patients had a Pericarbon valve implanted 
      in the aortic position. The mean age was 75+/-5 years. Seventy-eight patients 
      (55%) were in New York Heart Association (NYHA) class III or IV. Sixty patients 
      (42%) had one or more concomitant procedures (51 coronary artery bypass grafting 
      [CABG], 7 carotid endarterectomies, 9 others). RESULTS: The hospital mortality 
      rate was 12% (17 of 143 patients). The follow-up was 100% complete and the median 
      time was 42 months (range, 2 to 79 months). There were 36 late deaths, 20 being 
      cardiac-related: 5 non-valve-related, 11 valve-related, and 4 sudden unexpected 
      deaths. The 5-year actuarial survival was 57%+/-5%. There were 6 early valve 
      failures related to a calcific stenosis at a median time of 36 months (range, 5 
      to 66 months). Three patients had to undergo another operation and one of these 
      patients died. One patient died the day before the planned reoperation and 2 
      patients are followed with a symptomatic aortic stenosis but refuse reoperation. 
      Freedom from structural deterioration was 93%+/-3% at 4 years. Echocardiographic 
      examination was obtained in 73 patients at a median time of 42 months (range, 4 
      to 79 months). Four additional asymptomatic patients were found to have 
      calcifications of their prosthesis. The 5-year freedom from thromboembolic events 
      and from endocarditis were, respectively, 87%+/-5% and 92%+/-3%. CONCLUSION: The 
      surprisingly high rate of early failure due to calcific stenosis and of 
      thromboembolic events of the Pericarbon valve implanted in the aortic position in 
      the elderly made us discontinue its use in our institution.
FAU - d'Udekem, Y
AU  - d'Udekem Y
AD  - Cliniques Universitaires Saint-Luc, Brussels, Belgium. dudekem@chir.ucl.ac.be
FAU - Pasquet, A
AU  - Pasquet A
FAU - El Khoury, G A
AU  - El Khoury GA
FAU - Nouwen, J
AU  - Nouwen J
FAU - Vanoverschelde, J L
AU  - Vanoverschelde JL
FAU - Robert, A
AU  - Robert A
FAU - Dion, R A
AU  - Dion RA
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Actuarial Analysis
MH  - Aged
MH  - *Aortic Valve/diagnostic imaging/surgery
MH  - Aortic Valve Stenosis/diagnostic imaging/etiology
MH  - Bioprosthesis/*adverse effects
MH  - Calcinosis/diagnostic imaging/etiology
MH  - Coronary Artery Bypass
MH  - Echocardiography
MH  - Endarterectomy, Carotid
MH  - Endocarditis/etiology
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Prosthesis/*adverse effects
MH  - Heart Valve Prosthesis Implantation/adverse effects
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Prosthesis Design
MH  - Prosthesis Failure
MH  - Reoperation
MH  - Risk Factors
MH  - Surface Properties
MH  - Survival Rate
MH  - Thromboembolism/etiology
EDAT- 1999/02/04 00:00
MHDA- 1999/02/04 00:01
CRDT- 1999/02/04 00:00
PHST- 1999/02/04 00:00 [pubmed]
PHST- 1999/02/04 00:01 [medline]
PHST- 1999/02/04 00:00 [entrez]
AID - S0003-4975(98)01031-5 [pii]
AID - 10.1016/s0003-4975(98)01031-5 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1998 Dec;66(6 Suppl):S139-42. doi: 
      10.1016/s0003-4975(98)01031-5.