PMID- 11384745 OWN - NLM STAT- MEDLINE DCOM- 20010719 LR - 20220331 IS - 0065-2571 (Print) IS - 0065-2571 (Linking) VI - 41 DP - 2001 TI - The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. PG - 189-207 FAU - Maeda, H AU - Maeda H AD - Department of Microbiology, Kumamoto University School of Medicine, 860-0811, Kumamoto, Japan. msmaedah@gpo.kumamoto-u.ac.jp LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - England TA - Adv Enzyme Regul JT - Advances in enzyme regulation JID - 0044263 RN - 0 (Polymers) SB - IM MH - Animals MH - Area Under Curve MH - Blood Pressure MH - Carcinoma, Hepatocellular/blood supply/pathology MH - *Drug Delivery Systems MH - Humans MH - Liver/metabolism MH - Liver Neoplasms/blood supply/pathology MH - Models, Biological MH - Neoplasms/*blood supply/*therapy MH - *Permeability MH - Polymers/therapeutic use MH - Time Factors MH - Tissue Distribution MH - Veins/metabolism RF - 59 EDAT- 2001/06/01 10:00 MHDA- 2001/07/20 10:01 CRDT- 2001/06/01 10:00 PHST- 2001/06/01 10:00 [pubmed] PHST- 2001/07/20 10:01 [medline] PHST- 2001/06/01 10:00 [entrez] AID - S0065257100000133 [pii] AID - 10.1016/s0065-2571(00)00013-3 [doi] PST - ppublish SO - Adv Enzyme Regul. 2001;41:189-207. doi: 10.1016/s0065-2571(00)00013-3.