PMID- 16839774
OWN - NLM
STAT- MEDLINE
DCOM- 20070726
LR  - 20071115
IS  - 1044-579X (Print)
IS  - 1044-579X (Linking)
VI  - 17
IP  - 3
DP  - 2007 Jun
TI  - Human neuroblastoma stem cells.
PG  - 241-7
AB  - Human neuroblastoma is an embryonic cancer of the neural crest. Cellular 
      heterogeneity is a characteristic feature of both tumors and derived cell lines. 
      Recent studies have revealed that both cell lines and tumors contain cancer stem 
      cells. In culture, these cells are self-renewing, multipotent, and highly 
      malignant; in tumors their frequency correlates with a worse prognosis. Their 
      identification and characterization should now permit a targeted approach to more 
      effective treatment of this often fatal childhood cancer.
FAU - Ross, Robert A
AU  - Ross RA
AD  - Laboratory of Neurobiology, Department of Biological Sciences, 441 East Fordham 
      Road, Fordham University, Bronx, NY 10458, USA. rross@fordham.edu
FAU - Spengler, Barbara A
AU  - Spengler BA
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20060517
PL  - England
TA  - Semin Cancer Biol
JT  - Seminars in cancer biology
JID - 9010218
SB  - IM
MH  - Humans
MH  - Neoplastic Stem Cells/*pathology
MH  - Neural Crest/pathology
MH  - Neuroblastoma/genetics/*pathology
RF  - 48
EDAT- 2006/07/15 09:00
MHDA- 2007/07/27 09:00
CRDT- 2006/07/15 09:00
PHST- 2006/04/25 00:00 [received]
PHST- 2006/04/27 00:00 [accepted]
PHST- 2006/07/15 09:00 [pubmed]
PHST- 2007/07/27 09:00 [medline]
PHST- 2006/07/15 09:00 [entrez]
AID - S1044-579X(06)00038-1 [pii]
AID - 10.1016/j.semcancer.2006.04.006 [doi]
PST - ppublish
SO  - Semin Cancer Biol. 2007 Jun;17(3):241-7. doi: 10.1016/j.semcancer.2006.04.006. 
      Epub 2006 May 17.