PMID- 18223356
OWN - NLM
STAT- MEDLINE
DCOM- 20080327
LR  - 20220331
IS  - 1075-2765 (Print)
IS  - 1075-2765 (Linking)
VI  - 15
IP  - 1
DP  - 2008 Jan-Feb
TI  - Lycopene in cancer prevention and treatment.
PG  - 66-81
LID - 10.1097/MJT.0b013e31804c7120 [doi]
AB  - Dietary intake of lycopene is inversely associated with the risk of many cancers. 
      Preclinical studies show that lycopene has potent in vitro and in vivo antitumor 
      effects, suggesting potential preventive and therapeutic roles for the compound. 
      However, clinical trials with lycopene have only recently been started, and 
      available clinical data preclude firm conclusions with regard to its use in 
      cancer prevention and treatment. Further mechanistic studies and randomized 
      controlled clinical intervention trials with lycopene involving cancer patients 
      are warranted.
FAU - Seren, Soley
AU  - Seren S
AD  - Department of Internal Medicine, Wayne State University, Barbara Ann Karmanos 
      Cancer Institute, Detroit, Michigan 48201, USA.
FAU - Lieberman, Ronald
AU  - Lieberman R
FAU - Bayraktar, Ulas D
AU  - Bayraktar UD
FAU - Heath, Elisabeth
AU  - Heath E
FAU - Sahin, Kazim
AU  - Sahin K
FAU - Andic, Fundagul
AU  - Andic F
FAU - Kucuk, Omer
AU  - Kucuk O
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Am J Ther
JT  - American journal of therapeutics
JID - 9441347
RN  - 0 (Anticarcinogenic Agents)
RN  - 36-88-4 (Carotenoids)
RN  - SB0N2N0WV6 (Lycopene)
SB  - IM
MH  - Animals
MH  - Anticarcinogenic Agents/*pharmacology/therapeutic use
MH  - Carotenoids/*pharmacology/therapeutic use
MH  - Clinical Trials as Topic
MH  - Diet
MH  - Drug Evaluation, Preclinical
MH  - Humans
MH  - Lycopene
MH  - Neoplasms/*drug therapy/prevention & control
RF  - 169
EDAT- 2008/01/29 09:00
MHDA- 2008/03/28 09:00
CRDT- 2008/01/29 09:00
PHST- 2008/01/29 09:00 [pubmed]
PHST- 2008/03/28 09:00 [medline]
PHST- 2008/01/29 09:00 [entrez]
AID - 00045391-200801000-00012 [pii]
AID - 10.1097/MJT.0b013e31804c7120 [doi]
PST - ppublish
SO  - Am J Ther. 2008 Jan-Feb;15(1):66-81. doi: 10.1097/MJT.0b013e31804c7120.