PMID- 18339348
OWN - NLM
STAT- MEDLINE
DCOM- 20080623
LR  - 20220419
IS  - 1474-4422 (Print)
IS  - 1474-4465 (Electronic)
IS  - 1474-4422 (Linking)
VI  - 7
IP  - 4
DP  - 2008 Apr
TI  - Paraneoplastic syndromes of the CNS.
PG  - 327-40
LID - 10.1016/S1474-4422(08)70060-7 [doi]
AB  - Major advances in the management of paraneoplastic neurologic disorders (PND) 
      include the detection of new antineuronal antibodies, the improved 
      characterisation of known syndromes, the discovery of new syndromes, and the use 
      of CT and PET to reveal the associated tumours at an early stage. In addition, 
      the definition of useful clinical criteria has facilitated the early recognition 
      and treatment of these disorders. In this article, we review some classic 
      concepts about PND and recent clinical and immunological developments, focusing 
      on paraneoplastic cerebellar degeneration, opsoclonus-myoclonus, and 
      encephalitides affecting the limbic system.
FAU - Dalmau, Josep
AU  - Dalmau J
AD  - Division of Neuro-oncology, Department of Neurology, University of Pennsylvania, 
      Philadelphia 19104, USA. josep.dalmau@uphs.upenn.edu
FAU - Rosenfeld, Myrna R
AU  - Rosenfeld MR
LA  - eng
GR  - R56 CA089054/CA/NCI NIH HHS/United States
GR  - R01 CA107192-04/CA/NCI NIH HHS/United States
GR  - 2R56-CA-089054/CA/NCI NIH HHS/United States
GR  - R01 CA107192/CA/NCI NIH HHS/United States
GR  - R01CA107192/CA/NCI NIH HHS/United States
GR  - R56 CA089054-06A1/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
PL  - England
TA  - Lancet Neurol
JT  - The Lancet. Neurology
JID - 101139309
SB  - IM
MH  - Central Nervous System/*pathology
MH  - Diagnostic Imaging/methods
MH  - Humans
MH  - *Paraneoplastic Syndromes, Nervous System/immunology/metabolism/pathology
PMC - PMC2367117
MID - NIHMS45999
EDAT- 2008/03/15 09:00
MHDA- 2008/06/24 09:00
PMCR- 2009/04/01
CRDT- 2008/03/15 09:00
PHST- 2008/03/15 09:00 [pubmed]
PHST- 2008/06/24 09:00 [medline]
PHST- 2008/03/15 09:00 [entrez]
PHST- 2009/04/01 00:00 [pmc-release]
AID - S1474-4422(08)70060-7 [pii]
AID - 10.1016/S1474-4422(08)70060-7 [doi]
PST - ppublish
SO  - Lancet Neurol. 2008 Apr;7(4):327-40. doi: 10.1016/S1474-4422(08)70060-7.