PMID- 20018966 OWN - NLM STAT- MEDLINE DCOM- 20100105 LR - 20221109 IS - 1533-4406 (Electronic) IS - 0028-4793 (Print) IS - 0028-4793 (Linking) VI - 361 IP - 25 DP - 2009 Dec 17 TI - Molecular origins of cancer: Molecular basis of colorectal cancer. PG - 2449-60 LID - 10.1056/NEJMra0804588 [doi] FAU - Markowitz, Sanford D AU - Markowitz SD AD - Department of Medicine and Ireland Cancer Center, Case Western Reserve University School of Medicine and Case Medical Center, Cleveland, USA. sxm10@cwru.edu FAU - Bertagnolli, Monica M AU - Bertagnolli MM LA - eng GR - R01 CA127306/CA/NCI NIH HHS/United States GR - R01 CA127306-03/CA/NCI NIH HHS/United States GR - HHMI/Howard Hughes Medical Institute/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - United States TA - N Engl J Med JT - The New England journal of medicine JID - 0255562 RN - 0 (Biomarkers, Tumor) SB - IM CIN - N Engl J Med. 2010 Apr 1;362(13):1245-6; author reply 1246-7. PMID: 20357292 CIN - N Engl J Med. 2010 Apr 1;362(13):1246; author reply 1246-7. PMID: 20364460 CIN - N Engl J Med. 2010 Apr 1;362(13):1246; author reply 1246-7. PMID: 20364461 MH - Biomarkers, Tumor MH - Colorectal Neoplasms/diagnosis/*genetics MH - DNA Methylation MH - DNA Repair MH - Genes, Tumor Suppressor/physiology MH - *Genetic Predisposition to Disease MH - Genome MH - Humans MH - *Mutation MH - Oncogenes/physiology MH - Signal Transduction/genetics PMC - PMC2843693 MID - NIHMS177087 EDAT- 2009/12/19 06:00 MHDA- 2010/01/06 06:00 PMCR- 2010/06/17 CRDT- 2009/12/19 06:00 PHST- 2009/12/19 06:00 [entrez] PHST- 2009/12/19 06:00 [pubmed] PHST- 2010/01/06 06:00 [medline] PHST- 2010/06/17 00:00 [pmc-release] AID - 361/25/2449 [pii] AID - 10.1056/NEJMra0804588 [doi] PST - ppublish SO - N Engl J Med. 2009 Dec 17;361(25):2449-60. doi: 10.1056/NEJMra0804588.