PMID- 20019184
OWN - NLM
STAT- MEDLINE
DCOM- 20100315
LR  - 20220331
IS  - 1525-2191 (Electronic)
IS  - 0002-9440 (Print)
IS  - 0002-9440 (Linking)
VI  - 176
IP  - 1
DP  - 2010 Jan
TI  - Liver regeneration after partial hepatectomy: critical analysis of mechanistic 
      dilemmas.
PG  - 2-13
LID - 10.2353/ajpath.2010.090675 [doi]
AB  - Liver regeneration after partial hepatectomy is one of the most studied models of 
      cell, organ, and tissue regeneration. The complexity of the signaling pathways 
      initiating and terminating this process have provided paradigms for regenerative 
      medicine. Many aspects of the signaling mechanisms involved in hepatic 
      regeneration are under active investigation. The purpose of this review is to 
      focus on the areas still not well understood. The review also aims to provide 
      insights into the ways by which current concepts of liver regeneration can 
      provide understanding regarding malfunction of the regenerative process in liver 
      diseases, such as acute liver failure.
FAU - Michalopoulos, George K
AU  - Michalopoulos GK
AD  - University of Pittsburgh, Department of Pathology, School of Medicine, S-410 
      Biomedical Science Tower, Pittsburgh, PA 15261, USA. michalopoulosgk@msx.upmc.edu
LA  - eng
GR  - UL1 TR000005/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Review
DEP - 20091217
PL  - United States
TA  - Am J Pathol
JT  - The American journal of pathology
JID - 0370502
RN  - 0 (Intercellular Signaling Peptides and Proteins)
SB  - IM
MH  - Animals
MH  - Biomechanical Phenomena
MH  - *Hepatectomy
MH  - Humans
MH  - Intercellular Signaling Peptides and Proteins/metabolism
MH  - Liver Regeneration/*physiology
MH  - Regional Blood Flow
MH  - Signal Transduction
PMC - PMC2797862
EDAT- 2009/12/19 06:00
MHDA- 2010/03/17 06:00
PMCR- 2011/01/01
CRDT- 2009/12/19 06:00
PHST- 2009/12/19 06:00 [entrez]
PHST- 2009/12/19 06:00 [pubmed]
PHST- 2010/03/17 06:00 [medline]
PHST- 2011/01/01 00:00 [pmc-release]
AID - S0002-9440(10)60317-3 [pii]
AID - AJPA60317 [pii]
AID - 10.2353/ajpath.2010.090675 [doi]
PST - ppublish
SO  - Am J Pathol. 2010 Jan;176(1):2-13. doi: 10.2353/ajpath.2010.090675. Epub 2009 Dec 
      17.