PMID- 20422104
OWN - NLM
STAT- MEDLINE
DCOM- 20101130
LR  - 20240322
IS  - 1460-4744 (Electronic)
IS  - 0306-0012 (Print)
IS  - 0306-0012 (Linking)
VI  - 39
IP  - 9
DP  - 2010 Sep
TI  - Rheological properties of peptide-based hydrogels for biomedical and other 
      applications.
PG  - 3528-40
LID - 10.1039/b919449p [doi]
AB  - Peptide-based hydrogels are an important class of biomaterials finding use in 
      food industry and potential use in tissue engineering, drug delivery and 
      microfluidics. A primary experimental method to explore the physical properties 
      of these hydrogels is rheology. A fundamental understanding of peptide hydrogel 
      mechanical properties and underlying molecular mechanisms is crucial for 
      determining whether these biomaterials are potentially suitable for 
      biotechnological uses. In this critical review, we cover the literature 
      containing rheological characterization of the physical properties of peptide and 
      polypeptide-based hydrogels including hydrogel bulk mechanical properties, 
      gelation mechanisms, and the behavior of hydrogels during and after flow (219 
      references).
FAU - Yan, Congqi
AU  - Yan C
AD  - Department of Materials Science and Engineering, Delaware Institute of 
      Biotechnology, University of Delaware, Newark, DE 19716, USA.
FAU - Pochan, Darrin J
AU  - Pochan DJ
LA  - eng
GR  - P20 RR017716/RR/NCRR NIH HHS/United States
GR  - P20 RR017716-07/RR/NCRR NIH HHS/United States
GR  - 5P20RR017716-07/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Review
DEP - 20100426
PL  - England
TA  - Chem Soc Rev
JT  - Chemical Society reviews
JID - 0335405
RN  - 0 (Hydrogels)
RN  - 0 (Peptide Fragments)
SB  - IM
MH  - Animals
MH  - *Drug Delivery Systems
MH  - Humans
MH  - Hydrogels/*chemistry
MH  - Peptide Fragments/*chemistry
MH  - *Rheology
MH  - *Tissue Engineering
PMC - PMC3104857
MID - NIHMS291439
EDAT- 2010/04/28 06:00
MHDA- 2010/12/14 06:00
PMCR- 2011/05/31
CRDT- 2010/04/28 06:00
PHST- 2010/04/28 06:00 [entrez]
PHST- 2010/04/28 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
PHST- 2011/05/31 00:00 [pmc-release]
AID - 10.1039/b919449p [doi]
PST - ppublish
SO  - Chem Soc Rev. 2010 Sep;39(9):3528-40. doi: 10.1039/b919449p. Epub 2010 Apr 26.