PMID- 20800018
OWN - NLM
STAT- MEDLINE
DCOM- 20120209
LR  - 20191111
IS  - 1000-467X (Print)
IS  - 1944-446X (Linking)
VI  - 29
IP  - 9
DP  - 2010 Sep
TI  - Recent progress in nanotechnology for cancer therapy.
PG  - 775-80
AB  - The application of nanotechnology significantly benefits clinical practice in 
      cancer diagnosis, treatment, and management. Especially, nanotechnology offers a 
      promise for the targeted delivery of drugs, genes, and proteins to tumor tissues 
      and therefore alleviating the toxicity of anticancer agents in healthy tissues. 
      This article reviews current nanotechnology platforms for anticancer drug 
      delivery, including polymeric nanoparticles, liposomes, dendrimers, nanoshells, 
      carbon nanotubes, superparamagnetic nanoparticles, and nucleic acid-based 
      nanoparticles [DNA, RNA interference (RNAi), and antisense oligonucleotide (ASO)] 
      as well as nanotechnologies for combination therapeutic strategies, for example, 
      nanotechnologies combined with multidrug-resistance modulator, ultrasound, 
      hyperthermia, or photodynamic therapy. This review raises awareness of the 
      advantages and challenges for the application of these therapeutic 
      nanotechnologies, in light of some recent advances in nanotechnologic drug 
      delivery and cancer therapy.
FAU - Tang, Mu-Fei
AU  - Tang MF
AD  - School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China.
FAU - Lei, Lei
AU  - Lei L
FAU - Guo, Sheng-Rong
AU  - Guo SR
FAU - Huang, Wen-Lin
AU  - Huang WL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Chin J Cancer
JT  - Chinese journal of cancer
JID - 101498232
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Dendrimers)
RN  - 0 (Drug Carriers)
RN  - 0 (Liposomes)
RN  - 0 (Magnetite Nanoparticles)
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Polymers)
SB  - IM
MH  - Antineoplastic Agents/administration & dosage/*therapeutic use
MH  - Dendrimers/therapeutic use
MH  - Drug Carriers
MH  - Drug Delivery Systems
MH  - Drug Resistance, Multiple/drug effects
MH  - Drug Resistance, Neoplasm/drug effects
MH  - Humans
MH  - Liposomes/therapeutic use
MH  - Magnetite Nanoparticles/therapeutic use
MH  - Nanoparticles/*therapeutic use
MH  - Nanoshells/therapeutic use
MH  - Nanotechnology/*trends
MH  - Nanotubes, Carbon
MH  - Neoplasms/*drug therapy
MH  - Polymers/therapeutic use
EDAT- 2010/08/31 06:00
MHDA- 2012/02/10 06:00
CRDT- 2010/08/31 06:00
PHST- 2010/08/31 06:00 [entrez]
PHST- 2010/08/31 06:00 [pubmed]
PHST- 2012/02/10 06:00 [medline]
AID - 1944-446X201009775 [pii]
AID - 10.5732/cjc.010.10075 [doi]
PST - ppublish
SO  - Chin J Cancer. 2010 Sep;29(9):775-80. doi: 10.5732/cjc.010.10075.