PMID- 20856220
OWN - NLM
STAT- MEDLINE
DCOM- 20101103
LR  - 20220410
IS  - 1529-2916 (Electronic)
IS  - 1529-2908 (Linking)
VI  - 11
IP  - 10
DP  - 2010 Oct
TI  - Macrophage plasticity and interaction with lymphocyte subsets: cancer as a 
      paradigm.
PG  - 889-96
LID - 10.1038/ni.1937 [doi]
AB  - Plasticity is a hallmark of cells of the myelomonocytic lineage. In response to 
      innate recognition or signals from lymphocyte subsets, mononuclear phagocytes 
      undergo adaptive responses. Shaping of monocyte-macrophage function is an 
      essential component of resistance to pathogens, tissue damage and repair. The 
      orchestration of myelomonocytic cell function is a key element that links 
      inflammation and cancer and provides a paradigm for macrophage plasticity and 
      function. A better understanding of the molecular basis of myelomonocytic cell 
      plasticity will open new vistas in immunopathology and therapeutic intervention.
FAU - Biswas, Subhra K
AU  - Biswas SK
AD  - Singapore Immunology Network, Agency for Science, Technology & Research, 
      Singapore. subhra_biswas@immunol.a-star.edu.sg
FAU - Mantovani, Alberto
AU  - Mantovani A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20100920
PL  - United States
TA  - Nat Immunol
JT  - Nature immunology
JID - 100941354
RN  - 0 (Cytokines)
SB  - IM
MH  - Animals
MH  - Cytokines/biosynthesis
MH  - Humans
MH  - Inflammation/immunology
MH  - Lymphocyte Subsets/*immunology
MH  - Macrophage Activation
MH  - Macrophages/*immunology/metabolism
MH  - Monocytes/immunology
MH  - Neoplasms/*immunology
EDAT- 2010/09/22 06:00
MHDA- 2010/11/04 06:00
CRDT- 2010/09/22 06:00
PHST- 2010/09/22 06:00 [entrez]
PHST- 2010/09/22 06:00 [pubmed]
PHST- 2010/11/04 06:00 [medline]
AID - ni.1937 [pii]
AID - 10.1038/ni.1937 [doi]
PST - ppublish
SO  - Nat Immunol. 2010 Oct;11(10):889-96. doi: 10.1038/ni.1937. Epub 2010 Sep 20.