PMID- 20972220 OWN - NLM STAT- MEDLINE DCOM- 20110428 LR - 20240323 IS - 1362-4962 (Electronic) IS - 0305-1048 (Print) IS - 0305-1048 (Linking) VI - 39 IP - Database issue DP - 2011 Jan TI - The European Nucleotide Archive. PG - D28-31 LID - 10.1093/nar/gkq967 [doi] AB - The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is Europe's primary nucleotide-sequence repository. The ENA consists of three main databases: the Sequence Read Archive (SRA), the Trace Archive and EMBL-Bank. The objective of ENA is to support and promote the use of nucleotide sequencing as an experimental research platform by providing data submission, archive, search and download services. In this article, we outline these services and describe major changes and improvements introduced during 2010. These include extended EMBL-Bank and SRA-data submission services, extended ENA Browser functionality, support for submitting data to the European Genome-phenome Archive (EGA) through SRA, and the launch of a new sequence similarity search service. FAU - Leinonen, Rasko AU - Leinonen R AD - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. rasko@ebi.ac.uk FAU - Akhtar, Ruth AU - Akhtar R FAU - Birney, Ewan AU - Birney E FAU - Bower, Lawrence AU - Bower L FAU - Cerdeno-Tarraga, Ana AU - Cerdeno-Tarraga A FAU - Cheng, Ying AU - Cheng Y FAU - Cleland, Iain AU - Cleland I FAU - Faruque, Nadeem AU - Faruque N FAU - Goodgame, Neil AU - Goodgame N FAU - Gibson, Richard AU - Gibson R FAU - Hoad, Gemma AU - Hoad G FAU - Jang, Mikyung AU - Jang M FAU - Pakseresht, Nima AU - Pakseresht N FAU - Plaister, Sheila AU - Plaister S FAU - Radhakrishnan, Rajesh AU - Radhakrishnan R FAU - Reddy, Kethi AU - Reddy K FAU - Sobhany, Siamak AU - Sobhany S FAU - Ten Hoopen, Petra AU - Ten Hoopen P FAU - Vaughan, Robert AU - Vaughan R FAU - Zalunin, Vadim AU - Zalunin V FAU - Cochrane, Guy AU - Cochrane G LA - eng GR - 085532/Wellcome Trust/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20101023 PL - England TA - Nucleic Acids Res JT - Nucleic acids research JID - 0411011 SB - IM MH - *Base Sequence MH - *Databases, Nucleic Acid MH - Europe MH - High-Throughput Nucleotide Sequencing MH - Molecular Sequence Annotation PMC - PMC3013801 EDAT- 2010/10/26 06:00 MHDA- 2011/04/29 06:00 PMCR- 2010/10/22 CRDT- 2010/10/26 06:00 PHST- 2010/10/26 06:00 [entrez] PHST- 2010/10/26 06:00 [pubmed] PHST- 2011/04/29 06:00 [medline] PHST- 2010/10/22 00:00 [pmc-release] AID - gkq967 [pii] AID - 10.1093/nar/gkq967 [doi] PST - ppublish SO - Nucleic Acids Res. 2011 Jan;39(Database issue):D28-31. doi: 10.1093/nar/gkq967. Epub 2010 Oct 23.