PMID- 21112561
OWN - NLM
STAT- MEDLINE
DCOM- 20110318
LR  - 20220311
IS  - 1875-9777 (Electronic)
IS  - 1875-9777 (Linking)
VI  - 7
IP  - 6
DP  - 2010 Dec 3
TI  - Tissue-resident adult stem cell populations of rapidly self-renewing organs.
PG  - 656-70
LID - 10.1016/j.stem.2010.11.016 [doi]
AB  - The epithelial lining of the intestine, stomach, and skin is continuously exposed 
      to environmental assault, imposing a requirement for regular self-renewal. 
      Resident adult stem cell populations drive this renewal, and much effort has been 
      invested in revealing their identity. Reliable adult stem cell biomarkers would 
      accelerate our understanding of stem cell roles in tissue homeostasis and cancer. 
      Membrane-expressed markers would also facilitate isolation of these adult stem 
      cell populations for exploitation of their regenerative potential. Here, we 
      review recent advances in adult stem cell biology, highlighting the promise and 
      pitfalls of the candidate biomarkers of the various stem cell populations.
CI  - Copyright (c) 2010 Elsevier Inc. All rights reserved.
FAU - Barker, Nick
AU  - Barker N
AD  - Hubrecht Institute, Utrecht, the Netherlands. nicholas.barker@imb.a-star.edu.sg
FAU - Bartfeld, Sina
AU  - Bartfeld S
FAU - Clevers, Hans
AU  - Clevers H
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cell Stem Cell
JT  - Cell stem cell
JID - 101311472
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adult Stem Cells/*cytology/metabolism
MH  - Animals
MH  - Biomarkers/metabolism
MH  - Cell Differentiation
MH  - Hematopoietic Stem Cells/cytology/metabolism
MH  - Humans
MH  - Neoplasms/metabolism
EDAT- 2010/11/30 06:00
MHDA- 2011/03/19 06:00
CRDT- 2010/11/30 06:00
PHST- 2010/08/20 00:00 [received]
PHST- 2010/09/08 00:00 [revised]
PHST- 2010/11/09 00:00 [accepted]
PHST- 2010/11/30 06:00 [entrez]
PHST- 2010/11/30 06:00 [pubmed]
PHST- 2011/03/19 06:00 [medline]
AID - S1934-5909(10)00638-7 [pii]
AID - 10.1016/j.stem.2010.11.016 [doi]
PST - ppublish
SO  - Cell Stem Cell. 2010 Dec 3;7(6):656-70. doi: 10.1016/j.stem.2010.11.016.