PMID- 21386835
OWN - NLM
STAT- MEDLINE
DCOM- 20110516
LR  - 20220410
IS  - 1546-170X (Electronic)
IS  - 1078-8956 (Linking)
VI  - 17
IP  - 3
DP  - 2011 Mar
TI  - The cancer stem cell: premises, promises and challenges.
PG  - 313-9
LID - 10.1038/nm.2304 [doi]
AB  - Over the last decade, the notion that tumors are maintained by their own stem 
      cells, the so-called cancer stem cells, has created great excitement in the 
      research community. This review attempts to summarize the underlying concepts of 
      this notion, to distinguish hard facts from beliefs and to define the future 
      challenges of the field.
FAU - Clevers, Hans
AU  - Clevers H
AD  - Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University 
      Medical Center Utrecht, Utrecht, The Netherlands. h.clevers@hubrecht.eu
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Nat Med
JT  - Nature medicine
JID - 9502015
SB  - IM
MH  - Animals
MH  - Humans
MH  - Mice
MH  - Neoplasms/*pathology
MH  - Neoplastic Stem Cells/*cytology
MH  - Xenograft Model Antitumor Assays
EDAT- 2011/03/10 06:00
MHDA- 2011/05/17 06:00
CRDT- 2011/03/10 06:00
PHST- 2011/03/10 06:00 [entrez]
PHST- 2011/03/10 06:00 [pubmed]
PHST- 2011/05/17 06:00 [medline]
AID - nm.2304 [pii]
AID - 10.1038/nm.2304 [doi]
PST - ppublish
SO  - Nat Med. 2011 Mar;17(3):313-9. doi: 10.1038/nm.2304.