PMID- 21839917
OWN - NLM
STAT- MEDLINE
DCOM- 20111014
LR  - 20220408
IS  - 1878-1551 (Electronic)
IS  - 1534-5807 (Linking)
VI  - 21
IP  - 2
DP  - 2011 Aug 16
TI  - Pericytes: developmental, physiological, and pathological perspectives, problems, 
      and promises.
PG  - 193-215
LID - 10.1016/j.devcel.2011.07.001 [doi]
AB  - Pericytes, the mural cells of blood microvessels, have recently come into focus 
      as regulators of vascular morphogenesis and function during development, 
      cardiovascular homeostasis, and disease. Pericytes are implicated in the 
      development of diabetic retinopathy and tissue fibrosis, and they are potential 
      stromal targets for cancer therapy. Some pericytes are probably mesenchymal stem 
      or progenitor cells, which give rise to adipocytes, cartilage, bone, and muscle. 
      However, there is still confusion about the identity, ontogeny, and progeny of 
      pericytes. Here, we review the history of these investigations, indicate emerging 
      concepts, and point out problems and promise in the field of pericyte biology.
CI  - Copyright (c) 2011 Elsevier Inc. All rights reserved.
FAU - Armulik, Annika
AU  - Armulik A
AD  - Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, 
      Karolinska Institute, SE-171 77 Stockholm, Sweden.
FAU - Genove, Guillem
AU  - Genove G
FAU - Betsholtz, Christer
AU  - Betsholtz C
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Dev Cell
JT  - Developmental cell
JID - 101120028
RN  - 0 (Collagen Type IV)
SB  - IM
MH  - Animals
MH  - Cell Differentiation/*physiology
MH  - Collagen Type IV/metabolism
MH  - Endothelium, Vascular/*cytology/embryology
MH  - Models, Biological
MH  - Neovascularization, Pathologic/pathology/*physiopathology
MH  - Neovascularization, Physiologic/*physiology
MH  - Pericytes/pathology/*physiology/ultrastructure
MH  - Signal Transduction/physiology
EDAT- 2011/08/16 06:00
MHDA- 2011/10/15 06:00
CRDT- 2011/08/16 06:00
PHST- 2011/08/16 06:00 [entrez]
PHST- 2011/08/16 06:00 [pubmed]
PHST- 2011/10/15 06:00 [medline]
AID - S1534-5807(11)00269-3 [pii]
AID - 10.1016/j.devcel.2011.07.001 [doi]
PST - ppublish
SO  - Dev Cell. 2011 Aug 16;21(2):193-215. doi: 10.1016/j.devcel.2011.07.001.