PMID- 22175760 OWN - NLM STAT- MEDLINE DCOM- 20120406 LR - 20220409 IS - 1468-1331 (Electronic) IS - 1351-5101 (Linking) VI - 19 IP - 1 DP - 2012 Jan TI - The economic cost of brain disorders in Europe. PG - 155-62 LID - 10.1111/j.1468-1331.2011.03590.x [doi] AB - BACKGROUND AND PURPOSE: In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, more accurate, and comprehensive 2010 estimates for 30 European countries. METHODS: One-year prevalence and annual cost per person of 19 major groups of disorders are based on 'best estimates' derived from systematic literature reviews by panels of experts in epidemiology and health economics. Our cost estimation model was populated with national statistics from Eurostat to adjust to 2010 values, converting all local currencies to Euros (euro), imputing cost for countries where no data were available, and aggregating country estimates to purchasing power parity-adjusted estimates of the total cost of brain disorders in Europe in 2010. RESULTS: Total European 2010 cost of brain disorders was euro798 billion, of which direct health care cost 37%, direct non-medical cost 23%, and indirect cost 40%. Average cost per inhabitant was euro5.550. The European average cost per person with a disorder of the brain ranged between euro285 for headache and euro30 000 for neuromuscular disorders. Total annual cost per disorder (in billion euro 2010) was as follows: addiction 65.7; anxiety disorders 74.4; brain tumor 5.2; child/adolescent disorders 21.3; dementia 105.2; eating disorders 0.8; epilepsy 13.8; headache 43.5; mental retardation 43.3; mood disorders 113.4; multiple sclerosis 14.6; neuromuscular disorders 7.7; Parkinson's disease 13.9; personality disorders 27.3; psychotic disorders 93.9; sleep disorders 35.4; somatoform disorder 21.2; stroke 64.1; and traumatic brain injury 33.0. CONCLUSION: Our cost model revealed that brain disorders overall are much more costly than previously estimated constituting a major health economic challenge for Europe. Our estimate should be regarded as conservative because many disorders or cost items could not be included because of lack of data. CI - (c) 2011 The Author(s). European Journal of Neurology (c) 2011 EFNS. FAU - Olesen, J AU - Olesen J AD - Department of Neurology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark. jeol@glo.regionh.dk FAU - Gustavsson, A AU - Gustavsson A FAU - Svensson, M AU - Svensson M FAU - Wittchen, H-U AU - Wittchen HU FAU - Jonsson, B AU - Jonsson B CN - CDBE2010 study group CN - European Brain Council LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Eur J Neurol JT - European journal of neurology JID - 9506311 SB - IM CIN - Eur J Neurol. 2012 Jan;19(1):4-5. doi: 10.1111/j.1468-1331.2011.03499.x. PMID: 21914051 MH - Brain Diseases/*economics/epidemiology MH - Europe/epidemiology MH - Health Care Costs/*statistics & numerical data MH - Humans FIR - Jordanova, Albena IR - Jordanova A FIR - Musayev, Amir IR - Musayev A FIR - Gustavsson, Anders IR - Gustavsson A FIR - Gabilondo, Andrea IR - Gabilondo A FIR - Maercker, Andreas IR - Maercker A FIR - Melin, Beatrice IR - Melin B FIR - Jonsson, Bengt IR - Jonsson B FIR - Walder, Bernhard IR - Walder B FIR - Gannon, Brenda IR - Gannon B FIR - Schlehofer, Brigitte IR - Schlehofer B FIR - Faravelli, Carlo IR - Faravelli C FIR - Allgulander, Christer IR - Allgulander C FIR - Ljungcrantz, Christina IR - Ljungcrantz C FIR - Jacobi, Corinna IR - Jacobi C FIR - Muresanu, Dafin F IR - Muresanu DF FIR - Hilton Jones, David IR - Hilton Jones D FIR - Ehler, Eda IR - Ehler E FIR - Beghi, Ettore IR - Beghi E FIR - Norwood, Fiona IR - Norwood F FIR - Aguilera, Francisco IR - Aguilera F FIR - Jacobi, Frank IR - Jacobi F FIR - Jacobi, Frank IR - Jacobi F FIR - Kobelt, Gisela IR - Kobelt G FIR - Meinlschmidt, Gunther IR - Meinlschmidt G FIR - Steinhausen, Hans-Christoph IR - Steinhausen HC FIR - Wittchen, Hans-Ulrich IR - Wittchen HU FIR - Verschuuren, Jan IR - Verschuuren J FIR - Vallat, Jean-Michel IR - Vallat JM FIR - Glaus, Jennifer IR - Glaus J FIR - Reese, Jens-Peter IR - Reese JP FIR - Olesen, Jes IR - Olesen J FIR - van Os, Jim IR - van Os J FIR - Bentzen, Joan IR - Bentzen J FIR - Alonso, Jordi IR - Alonso J FIR - Garcia-Ibanez, Jose IR - Garcia-Ibanez J FIR - Dams, Judith IR - Dams J FIR - Rehm, Jurgen IR - Rehm J FIR - Lauer, Klaus IR - Lauer K FIR - von Wild, Klaus IR - von Wild K FIR - Karampampa, Korinna IR - Karampampa K FIR - Stovner, Lars Jacob IR - Stovner LJ FIR - Vecsei, Laszlo IR - Vecsei L FIR - Fratiglioni, Laura IR - Fratiglioni L FIR - van den Berg, Leonard H IR - van den Berg LH FIR - Jonsson, Linus IR - Jonsson L FIR - Salvador-Carulla, Luis IR - Salvador-Carulla L FIR - Perrin, Marc IR - Perrin M FIR - Milenkova, Maria IR - Milenkova M FIR - Knapp, Martin IR - Knapp M FIR - Preisig, Martin IR - Preisig M FIR - Moscarelli, Massimo IR - Moscarelli M FIR - Ekman, Mattias IR - Ekman M FIR - Linde, Mattias IR - Linde M FIR - Pugliatti, Maura IR - Pugliatti M FIR - Svensson, Mikael IR - Svensson M FIR - Rogers, Mohamed Mhadi IR - Rogers MM FIR - Tenovuo, Olli IR - Tenovuo O FIR - Van den Bergh, Peter IR - Van den Bergh P FIR - Azouvi, Philippe IR - Azouvi P FIR - Vos, Pieter IR - Vos P FIR - Jennum, Poul IR - Jennum P FIR - Martinez-Leal, Rafael IR - Martinez-Leal R FIR - Dodel, Richard IR - Dodel R FIR - Simon, Roland IR - Simon R FIR - Lieb, Roselind IR - Lieb R FIR - Drabsch, Stefanie IR - Drabsch S FIR - Otero, Susana IR - Otero S FIR - Kurth, Tobias IR - Kurth T FIR - Xu, Weili IR - Xu W FIR - Winter, Yaroslav IR - Winter Y EDAT- 2011/12/20 06:00 MHDA- 2012/04/07 06:00 CRDT- 2011/12/20 06:00 PHST- 2011/12/20 06:00 [entrez] PHST- 2011/12/20 06:00 [pubmed] PHST- 2012/04/07 06:00 [medline] AID - 10.1111/j.1468-1331.2011.03590.x [doi] PST - ppublish SO - Eur J Neurol. 2012 Jan;19(1):155-62. doi: 10.1111/j.1468-1331.2011.03590.x.