PMID- 23116311
OWN - NLM
STAT- MEDLINE
DCOM- 20130822
LR  - 20220408
IS  - 1873-4286 (Electronic)
IS  - 1381-6128 (Linking)
VI  - 19
IP  - 11
DP  - 2013
TI  - A review of therapeutic effects of curcumin.
PG  - 2032-46
AB  - There is a growing interest in herbal medicine. Scientific studies have 
      demonstrated the beneficial pharmacological effects of curcumin. Curcumin is a 
      bright yellow spice, derived from the rhizome of Curcuma longa Linn. It has been 
      proven that curcumin is a highly pleiotropic molecule which can be a modulator of 
      intracellular signaling pathways that control cell growth, inflammation, and 
      apoptosis. Curcumin might be a potential candidate for the prevention and/or 
      treatment of some diseases due to its anti-oxidant, antiinflammatory activities 
      and an excellent safety profile. We present an updated concise review of 
      currently available animal and clinical studies demonstrating the therapeutic 
      effect of curcumin.
FAU - Noorafshan, Ali
AU  - Noorafshan A
AD  - Histomorphometry & Stereology Research Center, Shiraz University of Medical 
      Sciences, Shiraz, Iran.
FAU - Ashkani-Esfahani, Soheil
AU  - Ashkani-Esfahani S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United Arab Emirates
TA  - Curr Pharm Des
JT  - Current pharmaceutical design
JID - 9602487
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Antineoplastic Agents, Phytogenic)
RN  - 0 (Antioxidants)
RN  - IT942ZTH98 (Curcumin)
SB  - IM
MH  - Animals
MH  - Anti-Inflammatory Agents/chemistry/pharmacokinetics/*therapeutic use
MH  - Antineoplastic Agents, Phytogenic
MH  - Antioxidants/chemistry/pharmacokinetics/*therapeutic use
MH  - Biological Availability
MH  - Curcumin/analogs & derivatives/chemistry/pharmacokinetics/*therapeutic use
MH  - Humans
MH  - Molecular Structure
MH  - Signal Transduction/drug effects
MH  - Structure-Activity Relationship
EDAT- 2012/11/03 06:00
MHDA- 2013/08/24 06:00
CRDT- 2012/11/03 06:00
PHST- 2012/08/31 00:00 [received]
PHST- 2012/10/22 00:00 [accepted]
PHST- 2012/11/03 06:00 [entrez]
PHST- 2012/11/03 06:00 [pubmed]
PHST- 2013/08/24 06:00 [medline]
AID - CPD-EPUB-20121023-6 [pii]
PST - ppublish
SO  - Curr Pharm Des. 2013;19(11):2032-46.