PMID- 24150413
OWN - NLM
STAT- MEDLINE
DCOM- 20131223
LR  - 20240321
IS  - 1476-4660 (Electronic)
IS  - 1476-1122 (Print)
IS  - 1476-1122 (Linking)
VI  - 12
IP  - 11
DP  - 2013 Nov
TI  - Strategies for advancing cancer nanomedicine.
PG  - 958-62
LID - 10.1038/nmat3792 [doi]
AB  - Cancer nanomedicines approved so far minimize toxicity, but their efficacy is 
      often limited by physiological barriers posed by the tumour microenvironment. 
      Here, we discuss how these barriers can be overcome through innovative 
      nanomedicine design and through creative manipulation of the tumour 
      microenvironment.
FAU - Chauhan, Vikash P
AU  - Chauhan VP
AD  - 1] Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts 
      General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [2] 
      Koch Institute for Integrative Cancer Research, Massachusetts Institute of 
      Technology, Cambridge, Massachusetts 02139, USA.
FAU - Jain, Rakesh K
AU  - Jain RK
LA  - eng
GR  - T32 CA073479/CA/NCI NIH HHS/United States
GR  - R01 CA126642/CA/NCI NIH HHS/United States
GR  - R01 CA163815/CA/NCI NIH HHS/United States
GR  - P01-CA080124/CA/NCI NIH HHS/United States
GR  - T32-CA073479/CA/NCI NIH HHS/United States
GR  - R01-CA163815/CA/NCI NIH HHS/United States
GR  - P01 CA080124/CA/NCI NIH HHS/United States
GR  - R01-CA126642/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Nat Mater
JT  - Nature materials
JID - 101155473
SB  - IM
MH  - Animals
MH  - Humans
MH  - Nanomedicine/*methods
MH  - Neoplasms/drug therapy/pathology/*therapy
MH  - Tumor Microenvironment/drug effects
PMC - PMC4120281
MID - NIHMS594118
EDAT- 2013/10/24 06:00
MHDA- 2013/12/24 06:00
PMCR- 2014/11/01
CRDT- 2013/10/24 06:00
PHST- 2013/10/24 06:00 [entrez]
PHST- 2013/10/24 06:00 [pubmed]
PHST- 2013/12/24 06:00 [medline]
PHST- 2014/11/01 00:00 [pmc-release]
AID - nmat3792 [pii]
AID - 10.1038/nmat3792 [doi]
PST - ppublish
SO  - Nat Mater. 2013 Nov;12(11):958-62. doi: 10.1038/nmat3792.