PMID- 2683077 OWN - NLM STAT- MEDLINE DCOM- 19891206 LR - 20190618 IS - 0036-8075 (Print) IS - 0036-8075 (Linking) VI - 246 IP - 4930 DP - 1989 Nov 3 TI - Dominoes and clocks: the union of two views of the cell cycle. PG - 614-21 AB - We review the recent advances in understanding transitions within the cell cycle. These have come from both genetic and biochemical approaches. We discuss the phylogenetic conservation of the mechanisms that induce mitosis and their implications for other transitions in the cell cycle. FAU - Murray, A W AU - Murray AW AD - Department of Physiology, School of Medicine, University of California, San Francisco 94143-0448. FAU - Kirschner, M W AU - Kirschner MW LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PT - Review PL - United States TA - Science JT - Science (New York, N.Y.) JID - 0404511 SB - IM MH - Animals MH - *Cell Cycle MH - *Genes, Regulator MH - Interphase MH - Mitosis MH - *Models, Biological MH - Models, Genetic MH - Time Factors RF - 114 EDAT- 1989/11/03 00:00 MHDA- 1989/11/03 00:01 CRDT- 1989/11/03 00:00 PHST- 1989/11/03 00:00 [pubmed] PHST- 1989/11/03 00:01 [medline] PHST- 1989/11/03 00:00 [entrez] AID - 10.1126/science.2683077 [doi] PST - ppublish SO - Science. 1989 Nov 3;246(4930):614-21. doi: 10.1126/science.2683077.