PMID- 2739723
OWN - NLM
STAT- MEDLINE
DCOM- 19890731
LR  - 20220224
IS  - 0028-0836 (Print)
IS  - 0028-0836 (Linking)
VI  - 340
IP  - 6228
DP  - 1989 Jul 6
TI  - Expression of a large family of POU-domain regulatory genes in mammalian brain 
      development.
PG  - 35-41
AB  - A novel region referred to as the POU-domain is present in two tissue-specific 
      transcription factors, Pit-1 and Oct-2, that activate expression of genes 
      specifying pituitary and lymphocyte phenotypes. We report the identification of 
      multiple new members of a large family of POU-domain genes expressed in adult 
      brain, and document that all the known mammalian POU-domain genes, including 
      Pit-1 and Oct-2, are expressed widely in the developing nervous system.
FAU - He, X
AU  - He X
AD  - Howard Hughes Medical Institute, University of California, San Diego, La Jolla 
      92093-0613.
FAU - Treacy, M N
AU  - Treacy MN
FAU - Simmons, D M
AU  - Simmons DM
FAU - Ingraham, H A
AU  - Ingraham HA
FAU - Swanson, L W
AU  - Swanson LW
FAU - Rosenfeld, M G
AU  - Rosenfeld MG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Nature
JT  - Nature
JID - 0410462
RN  - 0 (Transcription Factors)
SB  - IM
EIN - Nature 1989 Aug 24;340(6235):662
MH  - Amino Acid Sequence
MH  - Animals
MH  - Brain/*embryology
MH  - *Gene Expression Regulation
MH  - *Genes
MH  - *Genes, Regulator
MH  - Humans
MH  - Molecular Sequence Data
MH  - Rats
MH  - Sequence Homology, Nucleic Acid
MH  - Spinal Cord/embryology
MH  - Transcription Factors/genetics
EDAT- 1989/07/06 00:00
MHDA- 1989/07/06 00:01
CRDT- 1989/07/06 00:00
PHST- 1989/07/06 00:00 [pubmed]
PHST- 1989/07/06 00:01 [medline]
PHST- 1989/07/06 00:00 [entrez]
AID - 10.1038/340035a0 [doi]
PST - ppublish
SO  - Nature. 1989 Jul 6;340(6228):35-41. doi: 10.1038/340035a0.