PMID- 2832152
OWN - NLM
STAT- MEDLINE
DCOM- 19880504
LR  - 20220511
IS  - 0261-4189 (Print)
IS  - 1460-2075 (Electronic)
IS  - 0261-4189 (Linking)
VI  - 6
IP  - 13
DP  - 1987 Dec 20
TI  - KP elements repress P-induced hybrid dysgenesis in Drosophila melanogaster.
PG  - 4125-35
AB  - Molecular and genetic analysis has revealed a specific P factor deletion 
      derivative (the KP element) which is able to repress P-induced hybrid dysgenesis. 
      All naturally occurring strains lacking the P cytotype (M') that were examined, 
      throughout the world contain up to 30 copies of KP per haploid genome together 
      with complete P factors. The KP element is derived from the P factor by an 
      internal deletion of 1753 bp removing nucleotides 808-2560 and is transcribed to 
      yield an abundant 0.8-kb poly(A)+ RNA with the coding capacity for an in-frame 
      207 amino acid polypeptide. Genetic crosses show that KP elements preferentially 
      accumulate in the presence of P factors and suppress hybrid dysgenesis. 
      Suppression is transmitted through both sexes and is thus distinct from the 
      maternally transmitted P cytotype mode of suppression. The spread of KP elements 
      is probably due to the continual selection of individuals with the highest 
      numbers of KP elements in which P-induced hybrid dysgenesis is suppressed.
FAU - Black, D M
AU  - Black DM
AD  - Department of Genetics, University of Cambridge, UK.
FAU - Jackson, M S
AU  - Jackson MS
FAU - Kidwell, M G
AU  - Kidwell MG
FAU - Dover, G A
AU  - Dover GA
LA  - eng
SI  - GENBANK/X06590
GR  - GM 36715/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - EMBO J
JT  - The EMBO journal
JID - 8208664
RN  - 0 (DNA Transposable Elements)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Crosses, Genetic
MH  - *DNA Transposable Elements
MH  - Drosophila melanogaster/*genetics
MH  - Female
MH  - Genetic Variation
MH  - Hybridization, Genetic
MH  - Infertility
MH  - Male
MH  - Molecular Sequence Data
MH  - *Mutation
PMC - PMC553895
EDAT- 1987/12/20 00:00
MHDA- 1987/12/20 00:01
PMCR- 1988/12/20
CRDT- 1987/12/20 00:00
PHST- 1987/12/20 00:00 [pubmed]
PHST- 1987/12/20 00:01 [medline]
PHST- 1987/12/20 00:00 [entrez]
PHST- 1988/12/20 00:00 [pmc-release]
AID - 10.1002/j.1460-2075.1987.tb02758.x [doi]
PST - ppublish
SO  - EMBO J. 1987 Dec 20;6(13):4125-35. doi: 10.1002/j.1460-2075.1987.tb02758.x.