PMID- 2878369
OWN - NLM
STAT- MEDLINE
DCOM- 19870113
LR  - 20071114
IS  - 0028-0836 (Print)
IS  - 0028-0836 (Linking)
VI  - 324
IP  - 6097
DP  - 1986 Dec 11-17
TI  - A molecular gradient in early Drosophila embryos and its role in specifying the 
      body pattern.
PG  - 537-45
AB  - After fertilization, the protein products of the Drosophila homeobox gene caudal 
      (cad) accumulate in a concentration gradient spanning the anteroposterior axis of 
      the developing embryo. Mutations in the cad gene that reduce or eliminate the 
      gradient cause abnormal zygotic expression of at least one segmentation gene 
      (fushi tarazu) and alter the global body pattern.
FAU - Macdonald, P M
AU  - Macdonald PM
FAU - Struhl, G
AU  - Struhl G
LA  - eng
GR  - 1PO1GM29301/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Nature
JT  - Nature
JID - 0410462
RN  - 0 (Insect Hormones)
SB  - IM
MH  - Animals
MH  - Blastoderm/analysis
MH  - Drosophila/anatomy & histology/embryology/*genetics
MH  - *Genes, Homeobox
MH  - Insect Hormones/analysis/genetics/*physiology
MH  - Mitosis
MH  - Mutation
EDAT- 1986/12/11 00:00
MHDA- 1986/12/11 00:01
CRDT- 1986/12/11 00:00
PHST- 1986/12/11 00:00 [pubmed]
PHST- 1986/12/11 00:01 [medline]
PHST- 1986/12/11 00:00 [entrez]
AID - 10.1038/324537a0 [doi]
PST - ppublish
SO  - Nature. 1986 Dec 11-17;324(6097):537-45. doi: 10.1038/324537a0.