PMID- 3051159 OWN - NLM STAT- MEDLINE DCOM- 19881107 LR - 20220330 IS - 0889-857X (Print) IS - 0889-857X (Linking) VI - 14 IP - 2 DP - 1988 Aug TI - Therapy in gout. PG - 441-57 AB - The effective management of patients with gout is outlined. The treatment of the acute attack, the prevention of recurrent episodes, and the dissolution of tophi, when present, are generally straightforward and associated with relatively few complications. Patients with a resistant acute attack, with extensive tophaceous deposition, or with allergy or toxicity to any of the standard drugs, present more complex treatment decisions. All agents must be used in an individualized manner for each patient with appropriate concern for risks as well as for benefit. FAU - Wallace, S L AU - Wallace SL AD - Department of Medicine, State University of New York Health Sciences Center, Brooklyn. FAU - Singer, J Z AU - Singer JZ LA - eng PT - Journal Article PT - Review PL - United States TA - Rheum Dis Clin North Am JT - Rheumatic diseases clinics of North America JID - 8708093 RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 268B43MJ25 (Uric Acid) RN - SML2Y3J35T (Colchicine) SB - IM MH - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use MH - Calculi/drug therapy/prevention & control MH - Colchicine/therapeutic use MH - Gout/*drug therapy/prevention & control MH - Humans MH - Recurrence MH - Uric Acid/blood RF - 82 EDAT- 1988/08/01 00:00 MHDA- 1988/08/01 00:01 CRDT- 1988/08/01 00:00 PHST- 1988/08/01 00:00 [pubmed] PHST- 1988/08/01 00:01 [medline] PHST- 1988/08/01 00:00 [entrez] PST - ppublish SO - Rheum Dis Clin North Am. 1988 Aug;14(2):441-57.