PMID- 3357014
OWN - NLM
STAT- MEDLINE
DCOM- 19880526
LR  - 20191101
IS  - 0270-6474 (Print)
IS  - 1529-2401 (Electronic)
IS  - 0270-6474 (Linking)
VI  - 8
IP  - 4
DP  - 1988 Apr
TI  - Proliferation and differentiation of rat neuroepithelial precursor cells in vivo.
PG  - 1144-51
AB  - Important features of adult neuronal number, location, and type are a consequence 
      of early embryonic events that occur before neurons have differentiated. We have 
      measured cell number during embryogenesis of the rat CNS. Markers that are 
      expressed in the proliferating neuronal precursor are required to study the 
      mechanisms controlling their proliferation and differentiation. By applying 
      immunohistochemistry, fluorescence-activated cell sorting, and 3H-thymidine 
      auto-radiography to dissociated rat CNS cells, we show that the monoclonal 
      antibody Rat 401 recognizes a cell population with proliferative, temporal, and 
      quantitative features expected of neuronal precursors.
FAU - Frederiksen, K
AU  - Frederiksen K
AD  - Departments of Biology and Brain Science, Whitaker College, Massachusetts 
      Institute of Technology, Cambridge 02139.
FAU - McKay, R D
AU  - McKay RD
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Neurosci
JT  - The Journal of neuroscience : the official journal of the Society for 
      Neuroscience
JID - 8102140
RN  - VC2W18DGKR (Thymidine)
SB  - IM
MH  - Animals
MH  - Cell Differentiation
MH  - Cell Division
MH  - Female
MH  - Flow Cytometry
MH  - Immunohistochemistry
MH  - Nervous System/*embryology
MH  - Neurons/*cytology
MH  - Pregnancy
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Thymidine/metabolism
PMC - PMC6569254
EDAT- 1988/04/01 00:00
MHDA- 1988/04/01 00:01
PMCR- 1988/10/01
CRDT- 1988/04/01 00:00
PHST- 1988/04/01 00:00 [pubmed]
PHST- 1988/04/01 00:01 [medline]
PHST- 1988/04/01 00:00 [entrez]
PHST- 1988/10/01 00:00 [pmc-release]
AID - 10.1523/JNEUROSCI.08-04-01144.1988 [doi]
PST - ppublish
SO  - J Neurosci. 1988 Apr;8(4):1144-51. doi: 10.1523/JNEUROSCI.08-04-01144.1988.