PMID- 4040369 OWN - NLM STAT- MEDLINE DCOM- 19850815 LR - 20190623 IS - 0006-2952 (Print) IS - 0006-2952 (Linking) VI - 34 IP - 14 DP - 1985 Jul 15 TI - Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion. PG - 2583-6 FAU - Hamilton, T C AU - Hamilton TC FAU - Winker, M A AU - Winker MA FAU - Louie, K G AU - Louie KG FAU - Batist, G AU - Batist G FAU - Behrens, B C AU - Behrens BC FAU - Tsuruo, T AU - Tsuruo T FAU - Grotzinger, K R AU - Grotzinger KR FAU - McKoy, W M AU - McKoy WM FAU - Young, R C AU - Young RC FAU - Ozols, R F AU - Ozols RF LA - eng PT - Journal Article PL - England TA - Biochem Pharmacol JT - Biochemical pharmacology JID - 0101032 RN - 1982-67-8 (Methionine Sulfoximine) RN - 5072-26-4 (Buthionine Sulfoximine) RN - 80168379AG (Doxorubicin) RN - GAN16C9B8O (Glutathione) RN - Q20Q21Q62J (Cisplatin) RN - Q41OR9510P (Melphalan) SB - IM MH - Buthionine Sulfoximine MH - Cell Line MH - Cell Survival/drug effects MH - Cisplatin/*pharmacology MH - Doxorubicin/metabolism/*pharmacology MH - Drug Resistance MH - Drug Synergism MH - Female MH - Glutathione/*metabolism MH - Humans MH - Melphalan/metabolism/*pharmacology MH - Methionine Sulfoximine/*analogs & derivatives/pharmacology MH - Ovarian Neoplasms/*drug therapy/pathology EDAT- 1985/07/15 00:00 MHDA- 1985/07/15 00:01 CRDT- 1985/07/15 00:00 PHST- 1985/07/15 00:00 [pubmed] PHST- 1985/07/15 00:01 [medline] PHST- 1985/07/15 00:00 [entrez] AID - 0006-2952(85)90551-9 [pii] AID - 10.1016/0006-2952(85)90551-9 [doi] PST - ppublish SO - Biochem Pharmacol. 1985 Jul 15;34(14):2583-6. doi: 10.1016/0006-2952(85)90551-9.