PMID- 6165588
OWN - NLM
STAT- MEDLINE
DCOM- 19810810
LR  - 20061115
IS  - 0014-2980 (Print)
IS  - 0014-2980 (Linking)
VI  - 11
IP  - 3
DP  - 1981 Mar
TI  - The rapid isolation of clonable antigen-specific T lymphocyte lines capable of 
      mediating autoimmune encephalomyelitis.
PG  - 195-9
AB  - The isolation and propagation of functional antigen-specific lines of T 
      lymphoblasts is described. These lines were found to recognize foreign or self 
      antigens in association with accessory cells of syngeneic major 
      histocompatibility complex genotype. Intravenous inoculation of a T cell reactive 
      only against myelin basic protein led to development of clinical paralysis in 
      syngeneic rats. Thus, it is possible to study biological function as well as 
      antigen specificity using T cell lines.
FAU - Ben-Nun, A
AU  - Ben-Nun A
FAU - Wekerle, H
AU  - Wekerle H
FAU - Cohen, I R
AU  - Cohen IR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Eur J Immunol
JT  - European journal of immunology
JID - 1273201
RN  - 0 (Epitopes)
SB  - IM
MH  - Animals
MH  - Cell Line
MH  - Clone Cells/*immunology
MH  - Encephalomyelitis, Autoimmune, Experimental/*immunology
MH  - Epitopes
MH  - Major Histocompatibility Complex
MH  - Rats
MH  - T-Lymphocytes/*immunology
EDAT- 1981/03/01 00:00
MHDA- 1981/03/01 00:01
CRDT- 1981/03/01 00:00
PHST- 1981/03/01 00:00 [pubmed]
PHST- 1981/03/01 00:01 [medline]
PHST- 1981/03/01 00:00 [entrez]
AID - 10.1002/eji.1830110307 [doi]
PST - ppublish
SO  - Eur J Immunol. 1981 Mar;11(3):195-9. doi: 10.1002/eji.1830110307.