PMID- 6259499 OWN - NLM STAT- MEDLINE DCOM- 19810521 LR - 20190821 IS - 0306-9877 (Print) IS - 0306-9877 (Linking) VI - 7 IP - 1 DP - 1981 Jan TI - Cell division in normal and transformed cells: the possible role of superoxide and hydrogen peroxide. PG - 21-42 AB - A unified theory of cell division is presented. This theory explains the division of both tumor cells and normal cells and involves superoxide radicals, hydrogen peroxide, glucose, cAMP, and cGMP. FAU - Oberley, L W AU - Oberley LW FAU - Oberley, T D AU - Oberley TD FAU - Buettner, G R AU - Buettner GR LA - eng PT - Journal Article PL - United States TA - Med Hypotheses JT - Medical hypotheses JID - 7505668 RN - 11062-77-4 (Superoxides) RN - BBX060AN9V (Hydrogen Peroxide) RN - E0399OZS9N (Cyclic AMP) RN - IY9XDZ35W2 (Glucose) RN - S88TT14065 (Oxygen) SB - IM MH - Animals MH - *Cell Division MH - Cell Membrane/physiology MH - Cell Survival MH - Cell Transformation, Neoplastic/*metabolism MH - Cyclic AMP/physiology MH - Glucose/metabolism MH - Glycolysis MH - Humans MH - Hydrogen Peroxide/*physiology MH - Liver/metabolism MH - Mitochondria/physiology MH - Models, Theoretical MH - Oxygen/*physiology MH - Sarcoma, Experimental/physiopathology MH - Superoxides/*physiology EDAT- 1981/01/01 00:00 MHDA- 1981/01/01 00:01 CRDT- 1981/01/01 00:00 PHST- 1981/01/01 00:00 [pubmed] PHST- 1981/01/01 00:01 [medline] PHST- 1981/01/01 00:00 [entrez] AID - 0306-9877(81)90018-9 [pii] AID - 10.1016/0306-9877(81)90018-9 [doi] PST - ppublish SO - Med Hypotheses. 1981 Jan;7(1):21-42. doi: 10.1016/0306-9877(81)90018-9.