PMID- 6366516
OWN - NLM
STAT- MEDLINE
DCOM- 19840425
LR  - 20210526
IS  - 0270-7306 (Print)
IS  - 1098-5549 (Electronic)
IS  - 0270-7306 (Linking)
VI  - 4
IP  - 2
DP  - 1984 Feb
TI  - Primary structure of the Saccharomyces cerevisiae GAL4 gene.
PG  - 260-7
AB  - The GAL4 gene encodes a positive regulator of the galactose-inducible genes in 
      Saccharomyces cerevisiae. Recently, GAL4 has been cloned and its 2.8-kilobase 
      mRNA has been identified. We report here the DNA sequence of GAL4 and the mapping 
      of the 5' and 3' ends of its transcripts. The region sequenced contains a single 
      open reading frame, 881 codons long, which could encode a 99,350-dalton protein. 
      The 5' ends of the GAL4 transcripts fall into two clusters. Transcripts which 
      begin at the upstream cluster would encode the 99,350-dalton protein, whereas 
      those starting at the downstream cluster may result in the synthesis of a 
      shorter, 91,600-dalton protein. The putative GAL4 proteins contain an amino acid 
      sequence near their amino termini which resembles a DNA-binding motif found in 
      bacterial and phage repressors and gene activator proteins.
FAU - Laughon, A
AU  - Laughon A
FAU - Gesteland, R F
AU  - Gesteland RF
LA  - eng
SI  - GENBANK/K01486
GR  - GM07531/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Mol Cell Biol
JT  - Molecular and cellular biology
JID - 8109087
RN  - 0 (DNA, Fungal)
RN  - 0 (Fungal Proteins)
RN  - 0 (RNA, Fungal)
RN  - X2RN3Q8DNE (Galactose)
SB  - IM
MH  - Amino Acid Sequence
MH  - Base Sequence
MH  - DNA, Fungal/isolation & purification
MH  - Fungal Proteins/biosynthesis/genetics
MH  - Galactose/*metabolism
MH  - *Genes, Fungal
MH  - RNA, Fungal/isolation & purification
MH  - Saccharomyces cerevisiae/*genetics
MH  - Transcription, Genetic
PMC - PMC368690
EDAT- 1984/02/01 00:00
MHDA- 1984/02/01 00:01
PMCR- 1984/02/01
CRDT- 1984/02/01 00:00
PHST- 1984/02/01 00:00 [pubmed]
PHST- 1984/02/01 00:01 [medline]
PHST- 1984/02/01 00:00 [entrez]
PHST- 1984/02/01 00:00 [pmc-release]
AID - 10.1128/mcb.4.2.260-267.1984 [doi]
PST - ppublish
SO  - Mol Cell Biol. 1984 Feb;4(2):260-7. doi: 10.1128/mcb.4.2.260-267.1984.