PMID- 6403867
OWN - NLM
STAT- MEDLINE
DCOM- 19830505
LR  - 20190617
IS  - 0028-0836 (Print)
IS  - 0028-0836 (Linking)
VI  - 302
IP  - 5906
DP  - 1983 Mar 24-30
TI  - Structure and expression of a cloned cDNA for human interleukin-2.
PG  - 305-10
AB  - A cDNA coding for human interleukin-2 (IL-2) has been cloned from a cDNA library 
      prepared from partially purified IL-2 mRNA. The DNA sequence codes for a 
      polypeptide which consists of 153 amino acids including a putative signal 
      sequence. A biologically active polypeptide, characteristic of human IL-2, was 
      produced when the cDNA was fused to a simian virus 40 promoter sequence and used 
      to transfect cultured monkey COS cells.
FAU - Taniguchi, T
AU  - Taniguchi T
FAU - Matsui, H
AU  - Matsui H
FAU - Fujita, T
AU  - Fujita T
FAU - Takaoka, C
AU  - Takaoka C
FAU - Kashima, N
AU  - Kashima N
FAU - Yoshimoto, R
AU  - Yoshimoto R
FAU - Hamuro, J
AU  - Hamuro J
LA  - eng
SI  - GENBANK/J00264
PT  - Journal Article
PL  - England
TA  - Nature
JT  - Nature
JID - 0410462
RN  - 0 (Interleukin-2)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Base Sequence
MH  - Cells, Cultured
MH  - Cloning, Molecular
MH  - DNA/genetics
MH  - Gene Expression Regulation
MH  - Haplorhini
MH  - Humans
MH  - Interleukin-2/*genetics
MH  - Operon
MH  - Plasmids
EDAT- 1983/03/24 00:00
MHDA- 1983/03/24 00:01
CRDT- 1983/03/24 00:00
PHST- 1983/03/24 00:00 [pubmed]
PHST- 1983/03/24 00:01 [medline]
PHST- 1983/03/24 00:00 [entrez]
AID - 10.1038/302305a0 [doi]
PST - ppublish
SO  - Nature. 1983 Mar 24-30;302(5906):305-10. doi: 10.1038/302305a0.